Project Grant R01DK144682
- The University of Southern California (USC) was awarded a $445,870 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, which runs from Sep 2, 2025 to Sep 1, 2027, will be used to develop a spatially patterned, mature, and functional human kidney organoid model by leveraging the plasticity of kidney progenitor cells. The goal is to overcome...
- The federal Project Grant award of $759,135 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research on the "Impact of Sex and Cell Death on Checkpoint Inhibitor Hepatotoxicity". The University of Southern California (USC) is the awardee and will conduct the research to investigate the mechanisms underlying immune-related liver injury resulting...
- The University of Southern California (USC) was awarded a $465,690 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the potential of urinary extracellular vesicles (UEVs) as a novel and safe therapy for autosomal recessive polycystic kidney disease (ARPKD). The research aims to characterize the nanoparticle properties and therapeutic cargo of UEVs, evaluate...
- This $2,833,514 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, titled "Renal Metabolism in AKI", will fund research to investigate changes in kidney metabolism in sepsis-associated acute kidney injury (AKI) and their impact on kidney tubule injury and recovery. The University of California, San Diego (UCSD) is the awardee...
- This $192,215 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research program) will support a research project titled "Assessing Patient-Centric Factors and Enhancing Risk Communication to Improve Treatment Persistence in Kidney and Cardiovascular Care" at the University of California, San Francisco (UCSF). The project aims to develop an effective risk communication aid to...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is providing $173,664 to The Regents of the University of California, San Francisco (UCSF) to conduct research on "Molecular Characterization of Ascites Fluid to Identify Drivers of Infection in Patients with Decompensated Cirrhosis." The project aims to apply metagenomic...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $1,023,404 to the University of South Carolina to study the role of cerebrovascular O-GlcNAcylation in predisposing diabetics to stroke, worsening post-stroke neurovascular injury, and impairing functional recovery. The research aims to determine if deficiency of the O-GlcNAc transferase (OGT) enzyme protects against pre-stroke parenchymal arteriole dysfunction...
- This federal Project Grant award of $246,750.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), with a project period from August 15, 2025 to August 14, 2027. The award supports research by The Trustees of Columbia University in the City of New York to investigate how obesity affects the function of macrophages and T cells in the pancreas, and their role...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $437,010 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of North Carolina at Chapel Hill. The grant, titled "Leveraging 'Smart Stent' Platform Technologies for AVF Maturation and More", aims to develop and test a biodegradable magnesium "smart stent" technology to improve early blood flow and minimize stenosis...
- This $108,294 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant recipient is The Medical University of South Carolina (MUSC), which will use the funding to identify novel glycomic biomarkers that can be detected in urine to monitor disease progression and predict treatment response in lupus nephritis, a serious kidney disease that affects...
The University of Southern California (USC) was awarded a $807,860 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, titled "STROKE VOLUME-BASED FLUID RESUSCITATION IN AP (SUSTAIN)", aims to address the critical knowledge gap in optimal fluid therapy administration for acute pancreatitis (AP) treatment. The project will compare an individualized, non-invasive, delta stroke-volume guided fluid therapy approach to a moderate weight-guided fluid therapy approach in patients with predicted severe AP. Additionally, the project will evaluate a phase-based paradigm for fluid resuscitation in AP. This award represents the first randomized clinical trial in AP patients to assess a patient-centric, physiologically guided fluid therapy strategy versus generic weight-based approaches. The project period runs from September 12, 2025 to September 11, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $807.9k | 9/11/25 |