Project Grant R01DK144066
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Virginia $782,459 on March 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the impact of obesity on microvascular insulin action and cardiorespiratory fitness in individuals with Type 1 Diabetes. The research will test the hypothesis that endothelial oxidative stress and microvascular insulin resistance lead to reduced skeletal and...
- The National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health under the Department of Health and Human Services, awarded $717,030 to the University of Virginia on May 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to uncover neural circuits controlling body weight and metabolism. The research develops and applies RAMPANT (rabies afferent mapping by poly-A nuclear transcriptomics), a novel...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Alabama at Birmingham $298,000 on August 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct a pilot trial evaluating a scalable behavioral intervention for weight loss maintenance after patients discontinue GLP-1 receptor agonists and anti-obesity medications. The study will enroll 64 participants in a randomized factorial design to assess a...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Virginia Polytechnic Institute & State University $132,885 on March 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). This is a K01 Mentored Research Scientist Development Award, a Project Grant assistance type supporting early-career investigator development. The award funds research by Dr. Mary Elizabeth Baugh, PhD, RD, investigating how obesity and insulin...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Alabama at Birmingham $743,243 on August 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct a sequential multiple assignment randomized trial optimizing intensive behavioral therapy for obesity in adults aged 50 to 75 years. The trial will enroll 250 adults with obesity to determine the optimal first-line diet strategy—high-protein versus...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a component of the Department of Health and Human Services National Institutes of Health, awarded the Regents of the University of Michigan $1,519,835 on September 24, 2025, to test a novel weight navigation program designed to overcome multilevel barriers to obesity treatment in primary care settings. The project grant (R01DK139094) supports research under the Diabetes, Digestive, and Kidney Diseases Extramural...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Duke University $790,119 on August 26, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate how memory formation in adipose tissue influences metabolic outcomes in obesity. The project, titled "Establishing Memory in Adipose Tissue Influences Future Metabolic Outcomes in Obesity," examines the mechanisms that drive divergent remodeling of white...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Virginia $797,878 on February 24, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the pathogenesis of concentric hypertrophy of kidney arterioles. The research examines how chronic stimulation of renin cells—triggered by renin-angiotensin system inhibitors or genetic mutations—leads to concentric arterial and arteriolar hypertrophy, a...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Virginia Commonwealth University $134,728 on December 12, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate hepato-skeletal crosstalk in metabolic dysfunction-associated steatotic liver disease (MASLD)-associated fracture susceptibility. The research uses the diet-induced animal model of NAFLD (DIAMOND) mouse to elaborate histologic bone changes and...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Virginia Commonwealth University $1.863 million on September 12, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct a feasibility and pilot study integrating a prescription produce program within a diabetes prevention program for type 2 diabetes prevention. The recipient will conduct a mixed-methods feasibility and pilot study using a randomized controlled trial...
The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Virginia $744,590 on August 21, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct a factorial experiment optimizing behavioral lifestyle intervention for adults prescribed next-generation anti-obesity medications. The project will recruit 608 adults with obesity or overweight with weight-related comorbidity who are prescribed second-generation anti-obesity medications by their healthcare providers. Over 12 months, researchers will randomize participants using an efficient 2×2×2×2×2 factorial trial design to receive or not receive five intervention components: an individual weight loss education and behavioral skills training session; three individual telephone coaching sessions; digital dietary self-monitoring with weekly automated feedback on calorie goal achievement; digital physical activity self-monitoring with weekly automated feedback on activity goal achievement; and digital weight self-monitoring with weekly automated feedback. The factorial design will identify which combination of intervention components optimally improves health outcomes in patients receiving anti-obesity medications, addressing the discordance between clinical trial implementations (which paired medications with lifestyle intervention) and real-world clinical practice (which typically provides minimal follow-up beyond dosage and side-effect management). Performance occurs in Charlottesville, Virginia, with a period of performance ending June 30, 2031. The award is classified as a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $744.6k | 8/20/26 |