The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $708,138 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Ann & Robert H. Lurie Children's Hospital of Chicago. The project aims to develop a biomechanically compatible small molecule-releasing scaffold to promote regeneration of bladder tissue, as an alternative to traditional enterocystoplasty surgical procedures which have significant complications. The research leverages the hospital's expertise in bladder tissue engineering, stem cell therapies, and animal models, with the goal of producing an anatomically and physiologically functional bladder tissue replacement. The award period runs from December 2024 through November 2028, supporting the development and evaluation of this novel bladder regeneration approach.
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