Project Grant R01DK139055
- This $203,676 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to evaluate patient priorities and the impact of cost on surgical preference for the treatment of benign prostatic hyperplasia (BPH). The key objectives are to: 1) identify the perioperative factors most important to patients undergoing BPH surgical intervention;...
- This federal Project Grant award of $690,451 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research on the role of bladder fibroblasts in regulating bladder function. The University of Pittsburgh will conduct studies to investigate the contractile properties of suburothelial fibroblasts and their contribution to the formation of bladder rugae, as well as the involvement of...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health, awarded a $106,395 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Washington. The grant, running from September 1, 2025 to August 31, 2030, aims to further the development of individuals into future surgeon-scientists engaged in urology research careers. Key objectives include providing medical...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $765,701 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Boston, Massachusetts. The grant, titled "Mapping Mechanosensory Circuits from the Bladder to Barrington's Nucleus," will fund research to explore the neural circuits that encode bladder fullness and control urination. The project...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $176,201 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of California, Irvine. The grant, with an award date of July 15, 2025 and an ultimate completion date of March 31, 2030, will fund research to investigate the molecular changes in aging female urethral striated muscle and develop potential treatments for urethral dysfunction,...
- This federal Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $3,005,541.00 to Baylor College of Medicine to conduct research on the mechanisms driving age-dependent and sex-dependent changes in bladder immunity that contribute to recurrent urinary tract infections (UTIs) and other lower urinary tract disorders in older women. The...
- The National Institute on Aging (NIA) awarded a $489,509 Project Grant (CFDA 93.866 - Aging Research) to the Magee-Womens Research Institute And Foundation to conduct research on steroid hormone pathways regulating benign prostate hyperplasia (BPH) and lower urinary tract symptoms (LUTS) associated with aging. The 2-year project aims to: Identify proteins and pathways involved in promoting smooth muscle relaxation and bladder voiding that are dysregulated in aged mouse prostate models and...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $320,778 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Vermont & State Agricultural College. The project, titled "PACAP/PAC1R Signaling and CRH Intersections in Micturition Circuits: Effects of Stress and Injury/Inflammation," will investigate how changes in central micturition and peripheral sensory circuits due to...
- This $148,986 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is funding research to investigate the role of BKγ subunits in regulating potassium secretion in the distal nephron. The research aims to improve understanding of the mechanisms underlying flow-induced potassium secretion, which is critical for maintaining whole-body potassium...
- This federal Project Grant award of $432,625 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The purpose of the grant is to create a dataset measuring urological function in 8 different rat strains at various life stages. This dataset, combined with previous data, will help researchers understand how urological function differs across rat strains and guide...
This $2,482,346 Project Grant was awarded on September 15, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research by the University of Pittsburgh to investigate the role of the ZC3H4 protein and mitochondrial dysfunction in the development of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) in aging men. The research aims to elucidate the mechanisms driving prostatic inflammation and fibrosis, which contribute to the pathophysiology of BPH/LUTS. The findings could inform the development of new treatments targeting the underlying metabolic and signaling pathways involved in this age-related condition. The project will be carried out over a 4-year period, with a scheduled completion date of August 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.5m | 9/5/25 |