This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $191,234 to Beth Israel Deaconess Medical Center, Inc. over the period of August 1, 2025 to July 31, 2030. The funding supports research to examine the role of gastric dopaminergic signaling and gastrointestinal mucosal injury in Parkinson's disease. Key objectives include investigating...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) provides $850,232 to Northwestern University to advance the evolution of the Chicago Classification for diagnosing esophageal motor disorders. The project aims to develop new approaches combining assessments of esophageal neuromyogenic function and geometry to identify biomechanical physiomarkers of...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) provides $594,956 to the University of South Florida to conduct research on the mechanisms underlying stretch-evoked activation of esophageal vagal afferents. The goal is to determine the mechanosensitive channels and sodium channels responsible for transducing esophageal stretch into vagal afferent...
This federal Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $747,500.00 to support research on memory formation in the enteric nervous system (ENS). The project aims to build the tools required for studying the formation and meaning of ENS memories, and then use these tools in combination with various perturbations to transform the...
This Project Grant award of $117,000.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research to investigate the role of substance P-mediated activation of mast cells in driving visceral hypersensitivity and barrier dysfunction in irritable bowel syndrome (IBS). The objective is to delineate the underlying mechanisms of bidirectional crosstalk between sensory...
This federal Project Grant award of $726,140.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant aims to elucidate the neural circuits and cellular mechanisms underlying visceral pain processing in the spinal cord and brainstem, with the goal of advancing understanding and treatment of visceral pain conditions such as irritable bowel syndrome,...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $1,000,100 Cooperative Agreement to The General Hospital Corporation (doing business as Massachusetts General Hospital) on September 1, 2024. The award will fund a consortium to study gut-brain communication in Parkinson's disease (PD). Key objectives include: Contributing PD patients and healthy controls to a...
This Project Grant award for $108,000.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant aims to enable medical students at the Medical University of South Carolina (MUSC) to participate in high-quality research on gastrointestinal (GI) and liver diseases during their medical school training. Specifically, the grant will (1) provide a focused...
The National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases awarded a $152,205 Project Grant to The Regents of the University of California San Francisco under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant funds research to investigate how vagal sensory neurons regulate autonomic responses to achieve metabolic homeostasis, and how downstream neuronal circuits in the nucleus tractus solitarius integrate...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $650,556 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to Northwestern University. The grant's objective is to develop an implantable sensor for chronically monitoring gastric motility in small animal models, leveraging recent advancements in stretchable bio-electronics. The specific aims are to: 1) create a miniature, wireless,...