The National Institute of Biomedical Imaging and Bioengineering awarded a $209,107 Project Grant (R21EB036732) to Northwestern University to develop an implantable, wireless sensor for chronic monitoring of gastric motility in small animal models. This research aims to improve understanding of brain-to-gut communication and address the lack of specialized tools to study gastrointestinal function. The two-year project, running from February 2025 to January 2028, will leverage recent advancements in stretchable bioelectronics to create the miniature sensor device. Additionally, the project will employ optogenetic and microfluidic techniques to manipulate and modulate stomach activity. This work is expected to introduce groundbreaking methodologies for exploring the neural regulation of gastric motility and provide insights to develop therapeutic strategies for digestive and metabolic disorders.
Generated 3/4/25, 6:26 AM