This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will provide approximately $107,987 to the Pennington Biomedical Research Center in Baton Rouge, Louisiana over a 5-year period from Sep 1, 2024 to Aug 31, 2029. The purpose of this grant is to host an annual 5-day "Clinical Methods for Nutrition and Obesity Research" course...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $1,618,520.00 to the University of Pittsburgh to conduct research on a novel lysosomal mechanism of adipocyte lipolysis. The project aims to define the molecular and cell biological mechanisms governing mobilization of fatty acids from adipocytes during fasting, as well as the role of the lysosomal...
This $464,985 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research to understand the regulation and consequences of extracellular vesicles (EVs) released from adipocytes (fat cells) in obesity-related cardiometabolic disease. The research, conducted by Washington University, aims to 1) determine how the production and release of adipocyte...
The National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) awarded a $355,111 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the Pennington Biomedical Research Center in Baton Rouge, Louisiana. The 5-year grant, running from August 1, 2024 to June 30, 2029, will fund research to better define the mechanisms of the glycophagy shunt and its role in cellular metabolism. The research aims to enhance understanding of glycogen metabolism,...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $124,536 to investigate the role of branched-chain amino acid (BCAA) metabolism in regulating adiposity during systemic hypoxia. The research aims to elucidate the mechanisms underlying the reprogramming of BCAA metabolism in adipose tissue under oxygen deprivation, and to determine the...
This federal Project Grant award for $107,250 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports research at the University of Oklahoma Health Sciences Center to investigate how developmental exposure to high omega-6 fatty acids impacts adipose stem cell fate and beige adipogenesis, with the goal of identifying novel mechanisms to promote...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $840,198 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Dana-Farber Cancer Institute, Inc. (Dfci) in Boston, MA. The goal of this 4-year project is to better understand the mechanisms of energy expenditure and adipose thermogenesis in mammalian systems, with a focus on the futile creatine cycle pathway. Key objectives include determining how...
This Project Grant award of $604,853 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) will fund research at Rockefeller University to elucidate the genetic determinants of human brown adipose tissue (BAT) function. The goal is to develop a better understanding of how BAT, which can protect against obesity and associated metabolic diseases, is regulated in humans. The research will leverage...
This Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research to understand the mechanisms by which glucocorticoid drugs induce insulin resistance and metabolic dysfunction in skeletal muscle. The $112,500 award, with a project period from September 1, 2024 to August 31, 2025, will be conducted by the Pennington Biomedical Research...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research to determine the developmental origins and regulation of dermal adipose tissue. The $121,875 award, granted on April 5, 2025, will be performed by the University of Pennsylvania and aims to: (1) elucidate the mechanisms by which the transcription factor BCL11B...