Project Grant R01DE036160
- The National Institute of Dental and Craniofacial Research, part of the National Institutes of Health under the Department of Health and Human Services, awarded The University of Chicago $328,000 on August 5, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop and validate a microsimulation model of oral health lifetime outcomes and resource use in older adults. The project, titled "Development and Validation of the U.S. Oral Health Microsimulation...
- The National Institute of Dental and Craniofacial Research awarded the University of Texas Health Science Center at Houston $721,776 on July 6, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to establish secure open access to the BIGMOUTH Dental Data Repository and develop an AI-powered research platform. The project, titled "OPENMOUTH: Leveraging AI to Enhance Fairness in Dental Clinical Research," will fully de-identify clinical data from the largest...
- The National Institute of Dental and Craniofacial Research awarded the University of Rochester $642,037 on August 6, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop and validate SmartTeeth++, an AI-powered digital platform for remote detection and prediction of early-stage oral diseases including dental caries and gingivitis. The project integrates computer vision, machine learning, biomedical engineering, and clinical dentistry to deliver three core...
- The National Institute of Dental and Craniofacial Research awarded the University of Alabama at Birmingham $666,812 under the Oral Diseases and Disorders Research program (CFDA 93.121) on July 14, 2026, for a multilevel retrospective cohort study examining the impacts of Medicaid dental benefits expansion on oral healthcare workforce composition and services delivery at federally qualified health centers. The research employs an event-study difference-in-differences design using Uniform Data...
- The National Institute of Dental and Craniofacial Research awarded The University of Chicago $133,239 on April 1, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop and deliver a research education program called Cultivating Researchers in Oral and Systemic Health Studies (CROSS). The program trains undergraduate students enrolled in colleges across the Chicago area in cross-disciplinary clinical research that integrates oral health, medicine, and the social...
- The National Institute of Dental and Craniofacial Research awarded The Regents of the University of California, San Francisco $328,000 on August 28, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop and validate an electronic health record–based phenotype of xerostomia and build a preliminary AI-driven risk prediction model for oral health complications. The project develops natural language processing methods to extract xerostomia cases and social risk...
- The National Institute of Dental and Craniofacial Research awarded the University of Texas Health Science Center at Houston $1,187,388 on May 15, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop, validate, and clinically evaluate PREDICT, an artificial intelligence-driven clinical decision support system for periodontitis diagnosis and risk stratification. Periodontitis affects 42 percent of U.S. adults and carries estimated misclassification rates of 32...
- The National Institute of Dental and Craniofacial Research, within the Department of Health and Human Services National Institutes of Health, awarded the University of Illinois $320,660 on July 9, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop anionic nanohybrid aggregate formulations for early childhood caries prevention. The project addresses early childhood caries affecting approximately 25 percent of American preschool children, particularly those of...
- The National Institute of Dental and Craniofacial Research awarded the University of Arizona $284,714 on July 8, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to conduct genomic analysis identifying therapeutic targets for HPV-associated oral cancers, specifically oropharyngeal squamous cell carcinoma driven by HPV16. The research uses gene co-expression network methods to study long non-coding RNAs (lncRNAs) and their regulatory roles across HPV16-driven cervical...
- The National Institute of Dental and Craniofacial Research awarded The University of Iowa $815,438 under the Oral Diseases and Disorders Research program on July 15, 2026. The award funds a longitudinal study investigating how a self-determination theory–based psychoeducational intervention affects oral microbial communities and early childhood caries risk factors in children from birth to three years of age. The research will compare oral metagenomic profiles between children receiving the...
The National Institute of Dental and Craniofacial Research awarded the University of Arizona $371,900 on August 3, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop innovative methods for evidence synthesis in oral health research. The project addresses barriers in current oral health evidence synthesis by developing oral-health-specific artificial intelligence tools, methodological resources, and analytical approaches. Aim 1 validates and adapts AI tools for study-eligibility assessment and structured data extraction using oral health gold-standard corpora, with outputs including high-recall screening models, field-level extraction with source-span provenance, and auditable operating procedures. Aim 2 builds a harmonized, living evidence resource from published oral health syntheses and derives predictive distributions for key parameters such as between-study heterogeneity and within-patient correlations to support principled analyses and realistic trial planning. Aim 3 develops Bayesian hierarchical models that explicitly address clustered designs common in dentistry, such as split-mouth trials and teeth within patients, to reduce uncertainty and improve precision. The period of performance extends from August 3, 2026, through July 31, 2031. Work is performed in Arizona.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $371.9k | 8/5/26 |