Project Grant R01DE035845
- The National Institute of Dental and Craniofacial Research awarded the University of Arizona $371,900 on August 3, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop innovative methods for evidence synthesis in oral health research. The project addresses barriers in current oral health evidence synthesis by developing oral-health-specific artificial intelligence tools, methodological resources, and analytical approaches. Aim 1 validates and adapts AI tools...
- The University of Rochester received a $1,000,000 project grant award from the National Science Foundation under the Computer and Information Science and Engineering program (CFDA 47.070). The grant will support the development of a smart, connected oral health community infrastructure utilizing artificial intelligence and digital technologies to address oral health disparities from tooth decay. The university will create and test a community-based model combining at-home smartphone use with...
- The National Institute of Dental and Craniofacial Research awarded the University of Texas Health Science Center at Houston $721,776 on July 6, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to establish secure open access to the BIGMOUTH Dental Data Repository and develop an AI-powered research platform. The project, titled "OPENMOUTH: Leveraging AI to Enhance Fairness in Dental Clinical Research," will fully de-identify clinical data from the largest...
- The National Institute of Dental and Craniofacial Research awarded the University of Texas Health Science Center at Houston $1,187,388 on May 15, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop, validate, and clinically evaluate PREDICT, an artificial intelligence-driven clinical decision support system for periodontitis diagnosis and risk stratification. Periodontitis affects 42 percent of U.S. adults and carries estimated misclassification rates of 32...
- The National Institute of Dental and Craniofacial Research awarded the University of Rochester $415,813 on July 7, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop a modular microphysiologic system (MPS) for culturing three-dimensional innervated salivary gland tissue mimetics in array format. The funded research will create a platform capable of static and optional perfused culture of organoids and tissues arranged in arrays, addressing a gap in current...
- The National Institute of Dental and Craniofacial Research awarded The Curators of the University of Missouri, doing business as University of Missouri at Kansas City, $527,533 on September 19, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop an AI-driven multimodal imaging system for risk stratification of oral potentially malignant disorders. The award funds development of machine learning and deep learning models that integrate Fourier-transform infrared...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research awarded $870,334 under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Research Foundation for the State University of New York for a project spanning August 1, 2025, through July 31, 2027. The project focuses on developing an early tooth organoid utilizing human induced pluripotent stem cells (iPSCs), addressing a critical gap in understanding early tooth development. The research...
- The National Institute of Dental and Craniofacial Research, part of the National Institutes of Health under the Department of Health and Human Services, awarded The University of Chicago $328,000 on August 5, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop and validate a microsimulation model of oral health lifetime outcomes and resource use in older adults. The project, titled "Development and Validation of the U.S. Oral Health Microsimulation...
- The National Institute of Dental and Craniofacial Research, within the Department of Health and Human Services National Institutes of Health, awarded the University of Illinois $320,660 on July 9, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop anionic nanohybrid aggregate formulations for early childhood caries prevention. The project addresses early childhood caries affecting approximately 25 percent of American preschool children, particularly those of...
- The National Institute of Dental and Craniofacial Research awarded the University of New Hampshire $299,950 on August 19, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop a functional smoothed deep learning approach combining deep neural networks and functional data analysis techniques for analyzing high-dimensional genetic data associated with orofacial clefts and predicting disease risk. The research will build and validate a functional smoothed deep...
The National Institute of Dental and Craniofacial Research awarded the University of Rochester $642,037 on August 6, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop and validate SmartTeeth++, an AI-powered digital platform for remote detection and prediction of early-stage oral diseases including dental caries and gingivitis. The project integrates computer vision, machine learning, biomedical engineering, and clinical dentistry to deliver three core technological components: a portable intraoral imaging platform enabling non-dental personnel to capture diagnostic-quality images in community settings; AI algorithms for detecting early-stage caries and gingivitis; and predictive modeling tools that combine imaging results with patient contextual data to forecast disease progression risk. Prior work supporting this award includes the eHygiene study (NIH X01DE030396), which demonstrated that non-dental personnel and patients can collect diagnostic-quality intraoral images suitable for remote assessment; the SmartTeeth study (NSF2238208), which incorporated intraoral imaging into obstetric visits and identified early-stage dental caries in 71.7% of patients lacking dental access; and the AICaries study (NIH R21DE030251), which developed preliminary AI models achieving over 89% sensitivity and 86% specificity for caries detection. The recipient has curated over 100,000 annotated intraoral images. Performance occurs in Rochester, New York. The period of performance extends from the award date through May 31, 2031. This assistance type is a project grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $642.0k | 8/10/26 |