Project Grant R01DE035831
- Federal Grant Award Summary Colorado State University's Sponsored Programs Division received a $300,155 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), effective August 1, 2025, through July 31, 2027. The award supports research into peptide discovery for osteogenesis to develop an off-the-shelf biomaterial capable of regenerating craniofacial bone defects without requiring exogenous...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded University of Colorado-Denver $156,000 through the Oral Diseases and Disorders Research program (CFDA 93.121) for a two-year project period beginning July 1, 2025 and concluding June 30, 2027. This Project Grant supports basic and translational research investigating sex-specific differences in the immune microenvironment of head and neck squamous cell carcinoma (HNSCC), an aggressive oral...
- Federal Grant Award Summary The Stowers Institute for Medical Research received a Project Grant award of $371,250 from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), effective March 1, 2026, through February 28, 2031. This five-year award supports fundamental research into the pathogenesis, phenotypic variation, and prevention of craniofacial anomalies—birth defects that account for approximately...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded the University of Illinois a Project Grant of $217,100.00 under the Oral Diseases and Disorders Research program (CFDA 93.121) effective March 1, 2030. This award supports a structured training and research initiative designed to develop the applicant as a clinician-scientist in craniofacial and oral sciences. The program delivers mentoring, career development support, and professional...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded Children's Research Institute a Project Grant of $384,578 under the Oral Diseases and Disorders Research program (CFDA 93.121), effective August 14, 2025, with a completion date of August 13, 2027. This research initiative focuses on identifying genomic regulatory elements involved in oral clefts by examining enhancers—DNA sequences critical to controlling gene expression during embryonic...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $2.74 million Project Grant to The Regents of the University of California (Lawrence Berkeley National Laboratory) beginning July 1, 2025, and concluding March 31, 2030, under the Oral Diseases and Disorders Research program (CFDA 93.121). This research initiative will produce a single-cell multimodal atlas of human craniofacial development to advance understanding of gene regulation in...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $162,281 Project Grant to the California Institute of Technology (Caltech) under the Oral Diseases and Disorders Research program (CFDA 93.121) to investigate the fundamental gene regulatory networks governing neural crest-derived bone formation. The research project, which commenced August 6, 2025 and concludes July 31, 2027, utilizes sturgeons as a unique model organism to...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $449,886 Project Grant to the University of California, Los Angeles, effective March 1, 2026, through February 28, 2031, under the Oral Diseases and Disorders Research program (CFDA 93.121). This research initiative focuses on elucidating the molecular and cellular mechanisms by which the MSX1 (MSH Homeobox 1) gene regulates early mandibular morphogenesis, with direct applications...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded The Johns Hopkins University a $521,362 Project Grant on August 12, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121) to investigate neuroimmune interactions in craniofacial bone healing. The research project, which extends through August 11, 2027, seeks to decode the signaling mechanisms between nerves, immune cells, and bone-forming cells during cranial bone repair....
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a Project Grant totaling $1.00 to The Johns Hopkins University on September 18, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121). The award supports research on "Generalizing Genome Editing for Rare Disease-Causing Variants" through August 31, 2028. The project develops generalizable genome editing strategies applicable to hundreds of rare disease-causing...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a Project Grant totaling $513,174 to The Regents of the University of Colorado-Denver for research on PDGFR (platelet-derived growth factor receptor) dimer-specific dynamics in the craniofacial mesenchyme. The award, effective May 1, 2026, through April 30, 2031, supports investigator-initiated basic and translational research under the Oral Diseases and Disorders Research program (CFDA 93.121). The research addresses critical gaps in understanding how differential internalization and trafficking dynamics of various PDGFR dimers regulate downstream intracellular signaling and cellular behavior during craniofacial development, with particular focus on neural crest cell migration and proliferation mechanisms relevant to birth defect prevention. The research project will employ a novel bimolecular fluorescence complementation approach to quantify internalization dynamics of ligand-receptor complexes for various PDGFR dimers in both in vitro and in vivo systems. This work is designed to advance fundamental knowledge of craniofacial morphogenesis and may contribute to prevention and treatment strategies for craniofacial birth differences, aligning with NIDCR's mission to translate dental, oral, and craniofacial research findings into improved health outcomes. The research will be conducted at the University of Colorado-Denver campus in Aurora, Colorado.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $513.2k | 4/28/26 |