This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $1,608,956 to The Regents of the University of California, operating as Lawrence Berkeley National Laboratory, to conduct research on human midface development and genetic factors underlying craniofacial birth defects. The key activities include: Generating a single-cell multimodal atlas of human craniofacial...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,325,889 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to the University of Southern California on September 19, 2024. This grant, titled "Regulating Skeletal Connectivity in Craniofacial Development and Disease," will support a comprehensive and forward-thinking research program led by Dr. Amy Merrill that investigates the craniofacial skeleton as a multi-tissue...
The National Institute of Dental and Craniofacial Research (NIDCR) has awarded a $148,176 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Regents of the University of California, Berkeley. The funding will support research to uncover novel gene regulatory networks underlying craniofacial development and specialization in pupfish species. The project aims to leverage the unique evolutionary model of Cyprinodon pupfishes on San Salvador Island to...
This Project Grant award of $3,069,994.00, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), supports a research program focused on investigating skeletal stem cell plasticity as a central mechanism underlying craniofacial bone diseases. The research aims to elucidate the roles of periosteal, endosteal, and chondrocyte stem cells in intramembranous and endochondral craniofacial bone...
This federal Project Grant award, valued at $294,000 and spanning September 2024 to September 2026, was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program. The grant supports research to understand the mechanisms of craniofacial cartilage differentiation from human neural crest stem cells, with the goal of developing tissue engineering approaches to repair birth defects and injuries to the head and...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $919,059 to The Regents of the University of California, San Francisco (UCSF) to conduct research on the role of the ESCRT (Endosomal Sorting Complexes Required for Transport) machinery in regulating craniofacial morphogenesis. The award period runs from September 16, 2024 to August 31, 2029. The research aims...
The University of Southern California (USC) was awarded a $7,748,000 Cooperative Agreement from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program. The award, titled "USC FACEBASE IV Craniofacial Development and Dysmorphology Data Management and Integration Hub (FACEBASE IV)," is for the period of August 15, 2024 to May 31, 2029. The goal of the FACEBASE IV project is to expand the comprehensive data...
This Project Grant award of $606,296 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will develop advanced 3D growth models of the craniofacial complex using state-of-the-art cone-beam computed tomography (CBCT) imaging. The models will incorporate a large, racially/ethnically diverse database of 40,000 CBCT images to analyze craniofacial growth patterns across age, sex, race, ethnicity, facial type,...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, is focused on studying the role of the SIX1 transcription factor in cell fate decisions within the mouse mandibular arch. The total funding amount is $315,289, with a project period from July 15, 2025 to July 14, 2027. The key objectives of this award are to: 1) Identify changes in cell populations within the mouse mandibular arch...
This federal Project Grant award of $503,648 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), supports research to investigate the genetic mechanisms driving the specification of oral/dental and skin lineages in the mandibular ectoderm. The research aims to determine how transcription factor interactions regulate these epithelial patterning processes, including identifying the chromatin-level regulation...