Project Grant R21DC022660
- The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $154,568 Project Grant (CFDA 93.173 - Research Related to Deafness and Communication Disorders) to the University of Southern California (USC) to conduct research on "Human Cochlear Masking and Suppression Measured Using Dynamic Stimuli." The award period runs from December 31, 2024 to June 30, 2025. Through this grant, USC will perform research to investigate solutions to problems relevant to...
- This federal Project Grant award for $486,750.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program. The grant supports research to explore the morphological changes and cell polarity mechanisms in supporting cells of the inner ear, which play a critical role in auditory function. The primary awardee, the Jackson Laboratory, a nonprofit biomedical research...
- The National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), awarded a $589,393 Project Grant to Northwestern University to support research on the development of cochlear innervation. The goal is to elucidate how the neural circuit in the mammalian cochlea assembles during development, by altering the identity of certain cell types involved. Through this project, the researchers will...
- The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded the University of Southern California (USC) a $456,500 Project Grant (CFDA 93.173) to develop a novel diagnostic test for sensory hearing loss. The "Gain-Sensitive Cochlear Microphonics" (GCM) test aims to assess the functional state and site of damage within the cochlear amplifier, which is crucial for hearing sensitivity and range. The proposed research will validate the GCM test in mice by comparing...
- This $647,518 Project Grant award, provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program, supports research investigating the impact of cochlear synaptopathy on brainstem mechanisms of monaural temporal processing and binaural hearing. The study aims to understand the neural mechanisms and loci in the auditory system that produce listening difficulties, which can emerge...
- The University of Pittsburgh received a $610,725 Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173) effective May 2, 2025 with a completion date of April 30, 2030. The project will characterize the physiological mechanisms contributing to "suprathreshold deficits" in sensorineural hearing loss, where individuals struggle to understand...
- This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $767,494 to the University of Miami to develop human inner ear organoid platforms for studying genetic hearing loss and vestibular disorders. The key objectives are to: 1) establish and optimize human induced pluripotent stem cell-derived 3D inner ear organoid systems from patients with...
- The National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA program "Research Related to Deafness and Communication Disorders", awarded a $193,750.00 Project Grant to The Johns Hopkins University. The grant, effective April 1, 2025 through March 31, 2028, will fund research to investigate the neural dynamics and underlying mechanisms in the auditory cortex during implicit learning of complex sounds. The research aims to map the neural circuits...
- This $115,158 Project Grant, awarded on February 1, 2025 by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research into the neurological mechanisms underlying hearing loss. The central hypothesis is that the presentation of phosphatidylserine acts as a signal to mark inactive spiral ganglion neuron connections with outer hair cells for removal, facilitating...
- This Project Grant award, titled "Epigenetic Mechanisms of Cochlear Damage and Repair," was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) federal grant program. The $652,216 award to Rutgers, The State University will support research to investigate the role of the CHD4 protein in maintaining hair cell identity and function in the cochlea. The 5-year project...
The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $410,534 Project Grant to The Medical University of South Carolina (MUSC) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The grant, awarded on September 10, 2025, seeks to identify genetic modifiers that influence the penetrance of hearing impairment in the context of Endothelin receptor EDNRB deficiency. The research aims to address the role of the KCNJ16 gene, which may influence hair cell excitability, as well as other candidate genes identified through a large-scale genome-wide association analysis using genetically diverse mouse models. The ultimate goal is to further the understanding of cellular and molecular mechanisms underlying variable hearing loss phenotypes, which could inform diagnostic, prognostic, and therapeutic strategies for congenital deafness and related communication disorders.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $410.5k | 9/10/25 |