Project Grant R01DA064359
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Massachusetts Medical School a $3.097 million Project Grant effective September 1, 2025, through May 31, 2030, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct "Improving Jail Response to the Overdose Crisis: A Hybrid Trial of Jail ECHO to Improve MOUD Implementation and Public Health Outcomes." The project addresses the critical gap in medication for...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Boston University Medical Campus $2.9 million under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and optimize a multicomponent behavioral intervention designed to improve buprenorphine treatment retention for individuals with opioid use disorder. The project, titled "BUP-BOOSTER: Behavioral Optimization for Overcoming Suboptimal Treatment Retention," will recruit 240 patients...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $1.5 million Project Grant to the University of Massachusetts Medical School on September 1, 2025, to conduct the "Improving Access to Medications for Opioid Use Disorder (MOUD) in Drug Courts Through Inter-Agency Collaboration: COLAAB Study" under the Drug Use and Addiction Research Programs (CFDA 93.279). The five-year project, concluding May 31, 2030, implements and evaluates a package of...
- Federal Grant Award Summary: Mass JCOIN II Clinical Research Hub The National Institute on Drug Abuse (NIDA) awarded the University of Massachusetts a $3.2 million Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) on September 1, 2025, to implement and evaluate the Massachusetts Justice Community Opioid Innovation Network Phase II (Mass JCOIN II) Clinical Research Hub through May 31, 2030. This research initiative builds upon successful Phase I findings that...
- Federal Grant Award Summary Boston Medical Center Corporation received a $2.67 million Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded May 1, 2026, for a four-year project period concluding April 30, 2030. The award funds development and implementation of LINK, a system-wide intervention designed to optimize utilization of medications for opioid use disorder (MOUD) and pre-exposure prophylaxis for HIV (PrEP)...
- This $777,565 Project Grant, awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), supports a research initiative at Columbia University's Health Sciences Division spanning from May 15, 2026, through February 28, 2031. The project uses data fusion methodology to analyze existing data from seven large medication for opioid use disorder (MOUD) trials conducted by the NIDA Clinical Trials Network. The research generates quantitative...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $197,640 Project Grant to Massachusetts General Hospital (MGH), effective March 1, 2026 through February 28, 2030, under the Drug Use and Addiction Research Programs (CFDA 93.279). This four-year research initiative will deliver clinical outcomes research and health economic analysis focused on integrating infectious disease (ID) care into rapid-access substance use disorder (SUD) bridge clinics. The project...
- Federal Project Grant Award Summary The National Institute on Drug Abuse awarded a $451,670 Project Grant to Massachusetts General Hospital (awarded May 15, 2026; completion April 30, 2028) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports preclinical evaluation and development of a novel Positron Emission Tomography (PET) neuroimaging probe, 18F-fluorocarfentanil (18F-FCFN), designed to safely and accessibly measure mu opioid receptor (MOR) activity in the...
- Federal Project Grant Award Summary Massachusetts General Hospital (MGH) received a $598,000 Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded March 15, 2026, with completion targeted for February 29, 2028. The grant funds research to uncover patterns in the evolving illicit drug supply and detect emerging overdose trends using advanced machine learning methods. The project addresses the critical need to identify...
- Federal Grant Award Summary The University of Massachusetts Medical School received a $1.74 million Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) awarded on July 15, 2025, with a completion date of March 31, 2030. This award funds research to discover and functionally characterize long non-coding RNAs (lncRNAs) in opioid use disorder (OUD) within the context of HIV at single-cell resolution. The project addresses a...
Tufts University School of Medicine received a $652,766 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) on May 1, 2026, with completion targeted for February 28, 2031. The Extended-Release Opioid Use Disorder Treatment in Massachusetts (EXOUD-MASS) project will conduct research to understand how extended-release buprenorphine (XRB) formulations can be optimally integrated into medication for opioid use disorder (MOUD) treatment options across Massachusetts healthcare venues. The research will examine perceived advantages and disadvantages of XRB formulations, identify factors influencing MOUD treatment selection decisions, and assess the geographic distribution of XRB access and utilization among individuals living with opioid use disorder. This research addresses a critical public health gap, as opioid-related overdose deaths have increased fourfold in Massachusetts since 2001, reaching over 2,000 annually. While MOUD medications including buprenorphine demonstrate significant effectiveness in reducing overdose risk by up to 59 percent, current U.S. MOUD coverage rates remain at 25 percent or less, compared to international benchmarks exceeding 50 percent. The project will generate evidence to enhance MOUD treatment adherence and accessibility, with particular focus on whether newly FDA-approved XRB formulations (approved 2017 and 2023) can improve treatment outcomes and retention compared to existing transmucosal buprenorphine options.EXOUD-MASS Project Grant Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $652.8k | 5/5/26 |