This Project Grant award of $1,383,618 from the National Institute on Drug Abuse (NIDA) under CFDA Program 93.279 - Drug Use and Addiction Research Programs supports research to investigate the microglia-mediated adverse effects of cannabis (specifically Delta-9-tetrahydrocannabinol or THC) on prefrontal cortex maturation and cognitive function during adolescence. The research aims to: 1) identify the time course of cannabinoid receptor type 1 (CNR1)-mediated molecular and morphological...
This $376,078 Project Grant awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will support research to explore the relationship between cannabis use for coping purposes and quantity/frequency of cannabis use. The 5-year study, set to commence on August 1, 2024, will be conducted by the University of Colorado. Key objectives include: Experimentally testing whether cannabis use increases after stress induction among...
The National Institute on Drug Abuse (NIDA) awarded a $1,980,270 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the Regents of the University of Minnesota. The award, which runs from September 30, 2024 to May 31, 2029, will fund an observational study to assess the neurobehavioral impacts of medical cannabis use in a sample of 120 patients aged 35-65 who are being treated for chronic pain in Minnesota. The study aims to evaluate the effects of medical...
This federal Project Grant award, ID R01DA059527, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The $2,118,992 grant will fund a prospective investigation into the effects of cannabis use on reward and pain neurocircuits in adolescents with depression. The research aims to understand the relationships between cannabis use and depression in adolescence, which may inform prevention and intervention strategies for...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $716,455.00 to the University of Washington to study the impacts of oral THC consumption during adolescence on adult mouse brain development and behavior. The key research objectives are to: 1) Determine how long-term adolescent use of THC-gelatin alone or in combination with CBD impacts cannabimimetic responses and natural...
The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $153,000 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to Washington State University. The grant, awarded on June 15, 2025, will fund a 24-month study examining the relationship between cannabis use and daily functioning in young adults with chronic pain. The research will use an ecological momentary assessment (EMA) design to capture real-time data on...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the federal Drug Use and Addiction Research Programs (CFDA 93.279), provides $242,310 to The Medical College of Wisconsin, Inc. to investigate the role of GQ signaling in mobilizing the endocannabinoid 2-arachidonoylglycerol (2-AG) by corticosterone in the prefrontal cortex. The research aims to enhance understanding of the mechanism by which corticosterone regulates endocannabinoid signaling and its impact on...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $233,250 to The Washington University in St. Louis to examine the relationship between early cannabis use and later opioid use disorder. The key objectives are to: 1) Estimate the association between early cannabis use and both proximal and distal aspects of opioid involvement, including whether the relationships are modified by co-occurring...
This federal Project Grant award of $360,100 was provided by the National Institute on Drug Abuse (NIDA), which administers the Drug Use and Addiction Research Programs (CFDA 93.279). The grant supports a research project titled "Socio-Structural Determinants of Cannabis and Derived Psychoactive Cannabis Product Use and Consequences Among Young Adults." The project will investigate the factors influencing the use of cannabis and derived psychoactive cannabis products, such as delta-8...
This $668,110 Project Grant awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund the development and acceptability testing of a technology-based intervention to reduce cannabis misuse among college students. The project aims to refine an existing intervention that provides information on cannabis products, marketing, laws, and risks to increase young adults' cannabis literacy. The research will involve focus groups with...
The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded a $621,186 Project Grant to the University of Wisconsin - Milwaukee (UWM). This 5-year grant, effective July 1, 2025, will fund a longitudinal study examining the impact of circulating endocannabinoid levels on neurocognition, impulsivity, and early cannabis use patterns in 2,000 youth enrolled in the Adolescent Brain Cognitive Development (ABCD) study. The research aims to establish the long-term effects of endocannabinoid signaling on brain development and substance use behaviors during critical adolescent years. Findings from this project could provide valuable insights into the role of the endocannabinoid system in neurodevelopment and associated risks for substance use disorders.