This $610,092 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) is designed to develop and test a hybrid substance use prevention program for upper elementary school students. The program will utilize a combination of online e-learning modules and traditional classroom sessions to teach students about the harms of vaping and the importance of safe prescription medication use. It will also focus on enhancing...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Federal Grant Program "Drug Use and Addiction Research Programs" (CFDA 93.279), provides $1,607,146 over 2 years to NDRI-USA Inc., a non-profit research organization based in New York. The funding will support the development of technology-based interventions to encourage drug checking, distribution of harm reduction supplies, and linkage to substance use services. The project aims to address the...
This Project Grant award, provided by the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund a 2-year R61 phase and 3-year R33 phase study to develop and test a multilevel substance use disorder (SUD) and overdose prevention strategy for rural youth involved in county legal systems. The R61 phase will collaboratively co-design the multilevel SUD/overdose prevention strategy and an implementation plan with rural county court systems,...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $668,110 to Washington State University to refine and assess the feasibility and acceptability of a technology-based intervention for college students. The intervention aims to increase young adults' knowledge of cannabis products, laws, and associated risks, in order to reduce cannabis misuse among college students. The study will involve focus...
The National Institute on Drug Abuse (NIDA) awarded a $264,000 project grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to Innovation Research And Training, Inc. (IRT), a woman-owned small business in Durham, North Carolina. The purpose of this 3-year project is to evaluate an interactive, multimedia, web-based, asynchronous training program called "Substance of Change: Building Assets in Mentees Affected by Substance Misuse" (SOC). The training is designed to...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to generate evidence that can inform effective prevention and treatment strategies for adolescent drug overdose. With $431,750 in funding over a 2-year period from September 2024 to September 2026, the project will: Estimate the prevalence of nonfatal adolescent drug overdose and identify high-risk demographic and clinical subgroups, stratified by drug...
This $311,000 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports the development and pilot testing of a novel mobile health (mHealth) intervention to reduce frequent and high-intensity cannabis use among young adults not attending college. The proposed "TAKE 5" intervention integrates online personalized feedback and tailored text messages to address five key domains related to cannabis use...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop efficient statistical methods for data fusion to improve the power and external validity of clinical trials for treating opioid use disorder. The $564,326 award, with a performance period from August 2024 to May 2029, will fund the development of new parametric and semiparametric estimators for average treatment effects,...
This $397,829 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Federal Drug Use and Addiction Research Programs (CFDA 93.279), supports the development of an AI platform to accelerate the discovery of therapeutics for substance use disorders (SUDs). The key objectives of this 1-year project are to: 1) create curated datasets and machine learning models to expedite drug discovery tasks, 2) identify mechanistic targets for GLP-1 receptor agonist pathways that can...
This $304,023 Project Grant awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports the development of a digital product called RESHAPE. The objective is to create a comprehensive digital experience that addresses the health-related social needs (HRSN) impacting substance use disorder (SUD) recovery. The project involves formative research, development, and large-scale deployment of the RESHAPE digital platform, which...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) provides $1,702,558 to Prevention Strategies, LLC to optimize an online behavioral intervention to prevent and reduce substance use among high school seniors.
The key objectives are to: 1) Design an initial set of six theory-based online intervention components targeting social influences linked to substance use; 2) Evaluate the effect of each component on its targeted mediating variables using a cluster-randomized optimization trial; 3) Revise less effective components; and 4) Evaluate the long-term efficacy of each revised component on substance use, related mediators, and secondary behavioral outcomes using a second cluster-randomized trial. This work aims to develop an efficient, optimized, and scalable substance use intervention that can be disseminated to high schools nationwide. The project will run from July 2024 through April 2029.