Project Grant R01AT013630
- The National Center for Complementary and Integrative Health awarded Vanderbilt University Medical Center $624,778 on August 31, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to conduct a multicenter feasibility clinical trial evaluating integrative health coaching for chronic low back pain in emergency department patients after discharge. The trial will test a randomized controlled design across multiple sites to assess whether remote...
- The National Institute on Aging awarded $735,047 to Vanderbilt University Medical Center on August 15, 2026, under the Aging Research program (CFDA 93.866) to conduct a randomized controlled trial testing a perioperative geriatric intervention for older adults undergoing major cancer surgery. The award funds a multicenter hybrid implementation-effectiveness trial enrolling 354 patients at two NCI-designated cancer centers. The intervention, called PERI-OP, consists of a preoperative in-person or...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the University of Arizona $1,149,088 on September 19, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to refine a computational surgical decision tool for vertebral body tethering (VBT), a growth-modulating surgical technique for correcting pediatric spinal deformities. The project develops and validates a patient-specific computational model to predict which children...
- The National Institute of Neurological Disorders and Stroke awarded the Regents of the University of Michigan a $6.827 million cooperative agreement on September 19, 2025, to conduct a Sequential Multiple Assignment Randomized Trial (SMART) evaluating personalized treatment algorithms for chronic low back pain across pharmacological, physical therapy, cognitive-behavioral, and mobile health self-management interventions. The University of Michigan's Back Pain Consortium Mechanistic Research...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the University of Washington $169,668 on July 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to develop and test tailored exercise interventions for patients with axial spondyloarthritis, with specific focus on addressing sex-based differences in disease outcomes. The award funds three specific research aims: quantifying the dose of physical activity that predicts...
- The National Heart, Lung, and Blood Institute awarded Vanderbilt University Medical Center $874,973 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct a randomized, placebo-controlled clinical trial of carnitine supplementation in pulmonary arterial hypertension (PAH) patients. The trial enrolls PAH patients across the United States via remote enrollment over a 12-week study period with quality-of-life improvement as the primary endpoint and...
- The National Center for Complementary and Integrative Health, part of the Department of Health and Human Services National Institutes of Health, awarded Duke University $444,125 on August 13, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to test the feasibility and acceptability of a psychological support and resource navigator program for orthopedic patients with high-impact chronic musculoskeletal pain. The navigator program addresses the...
- The National Institute of Child Health and Human Development awarded the University of Washington $616,250 on September 1, 2026, through the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a randomized controlled trial evaluating non-invasive spinal cord stimulation combined with intensive treadmill training to reduce spasticity and improve mobility in children with cerebral palsy. The research will enroll children with cerebral palsy in a 24-session...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Texas at Austin $581,518 on July 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a biomechanics-aware, image-guided surgical robotic workstation for minimally invasive spinal fixation. The project encompasses three integrated components: a biomechanics-aware design and planning module that uses quantitative computed...
- The National Institute of Neurological Disorders and Stroke awarded Yale University $4.17 million on August 25, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop a biopsychosocial model for peripheral artery disease pain management that integrates vascular interventions with psychological and behavioral assessment. The project develops novel MRI protocols to evaluate blood flow, muscle and nerve microstructure, and metabolism in patients with peripheral artery...
The National Institutes of Health Office of the Director awarded Vanderbilt University Medical Center $891,026 on August 1, 2026, under Trans-NIH Research Support (CFDA 93.310) to conduct a randomized controlled trial of a physical activity intervention for patients undergoing lumbar spine surgery. The award funds PASS (Physical Activity Intervention to Improve Surgical Spine Outcomes), a mind-body intervention combining brief action planning, motivational interviewing, pain coping skills, and wearable technology feedback to increase physical activity and improve long-term pain and functional outcomes after spine surgery. Prior pilot work demonstrated that patients who walk early after spine surgery achieve meaningful improvement in pain, disability, and opioid use. The trial will recruit 220 adults with degenerative lumbar spine conditions at three high-volume medical centers in the Southeast, Northeast, and Pacific Northwest regions. Eligible patients will be randomized after surgery to receive either eight weekly web-based sessions of PASS delivered by a physical therapist or standard-of-care physical activity education. Remote assessments will occur before surgery and at 6 and 12 months post-surgery, conducted by an evaluator blinded to randomization assignment. Performance of work occurs at Vanderbilt University Medical Center in Forest Hills, Tennessee. The period of performance extends from August 1, 2026, through July 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $891.0k | 7/31/26 |