The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $3,565,780 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop a groundbreaking high frequency trans-spinal magnetic stimulation (HF-TSMS) system for the non-invasive treatment of neuropathic pain. The project aims to refine the HF-TSMS technology to target neural pathways involved in...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $2,314,276 to Emory University to develop and test novel methods for delivering and assessing nociceptive-specific (pain-specific) stimuli in both pain-free individuals and those with fibromyalgia. The project aims to overcome limitations in current experimental pain testing by identifying skin regions devoid of innocuous...
This $4.7 million project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will support the development of electrophysiological and ultrasound quantitative biomarkers for myofascial pain syndrome. The grant to Beth Israel Deaconess Medical Center will establish the use of electrical impedance myography, myofiber threshold tracking excitability testing, and ultrasound shear wave elastography to assess differences between patients with active...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $200,000 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to The Spaulding Rehabilitation Hospital Corporation, a non-profit hospital and academic medical center in Boston, MA. The project, titled "Self-Regulation of Real-Time fMRI Brain Activity in Chronic Pain: A Potential Neurobiological Mechanism of Cognitive Behavioral Therapy," aims to investigate the...
This federal Project Grant award, totaling $4,572,599 and awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to elucidate the neural mechanisms by which colored light can produce analgesia (pain relief) for chronic musculoskeletal pain conditions, including fibromyalgia. The key products and services to be delivered under this multi-year grant include: 1) Identifying the specific retinal ganglion...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $898,025 to the University of Cincinnati to evaluate the use of transcutaneous spinal direct current stimulation (tsDCS) to modulate spinal interoceptive pathways (SIPs) and assess their role and therapeutic potential in major depressive disorder (MDD). The award supports a two-phase research study. In the R61 phase, the researchers will use...
This $14.2 million project grant from the National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, will fund research from September 2022 to August 2025 under the Drug Abuse and Addiction Research Programs (CFDA 93.279). The Massachusetts General Hospital will investigate the mechanisms by which spinal cord stimulation reduces pain, with the goal of improving device design and patient selection. Researchers will apply specialized nerve...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $6,522,833 Project Grant to The Leland Stanford Junior University to conduct a mechanistic randomized clinical trial investigating the central and peripheral nervous system mechanisms of pain relief induced by peripheral nerve stimulation (PNS) for the treatment of refractory chronic neuropathic pain. The 3-year study, funded under the NIH HEAL Initiative's CFDA 93.279 Drug Abuse and Addiction Research Programs, aims...
This $682,950 Project Grant award from the National Center for Complementary and Integrative Health (NCCIH) under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) will fund a feasibility study to evaluate the potential benefits of combining mindfulness-based stress reduction (MBSR) and open-label placebo (OLP) treatment for chronic pain management. The study, to be conducted by Arizona State University, will randomly assign 45 participants to one of three...
The National Center for Complementary and Integrative Health (NCCIH) awarded a $817,330 Project Grant (CFDA 93.213 - Research and Training in Complementary and Integrative Health) to the Rector & Visitors of the University of Virginia (UVA) to evaluate an adaptive intervention to improve pain outcomes following cognitive behavioral therapy for insomnia in patients with comorbid chronic low back pain and insomnia. The project aims to determine if adding a positive affect enhancing...