This $497,083 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports research to elucidate the genetic and molecular basis of scarless, multi-lineage skin regeneration in fetal mice. The project aims to create comprehensive cellular and molecular atlases of fetal versus postnatal wound healing processes using single-cell multiomics approaches. The...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $172,700 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to the University of California, Irvine. The project aims to develop a novel therapeutic approach for improving angiogenesis (blood vessel growth) during wound healing by delivering apoptotic (dying) neutrophils within a degradable hydrogel scaffold. This is expected to stimulate an immune response in...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $306,324 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to the Oklahoma Medical Research Foundation (OMRF) for the project "Deciphering the Myofibroblast Life Cycle in Skin Wound Healing". The grant, with a period of performance from September 1, 2024 to March 31, 2027, will fund research to create a molecular map of the myofibroblast life cycle and...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $626,879 in funding to the University of Southern California (USC) to conduct research into the cellular and molecular mechanisms that enable large-scale bone regeneration. The research aims to unravel the intricate processes governing the initiation and coordination of bone repair...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will provide $607,398 to Albany Medical College to investigate the role of the epidermal integrin α3β1 in age-related impairments to wound healing. The research aims to determine how waning integrin function in aging skin contributes to deficiencies in epidermal cell proliferation, migration, and...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $551,685 Project Grant (R01AR083352) to Duke University under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant funds research to investigate the role of desmosomes, cell adhesion structures, in regulating mRNA localization and translational processes. The research aims to determine the molecular mechanisms by which desmosomes recruit mRNAs and translational...
This federal Project Grant award, totaling $242,310, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant supports research at Rockefeller University to investigate the long-term systemic consequences of type 2 skin inflammation on epithelial stem cells. Specifically, the research aims to define the cellular mechanisms that distinguish inflammatory...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $220,224 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to The Regents of the University of Colorado (CU) to develop "Granular Hydrogels for the Controlled Delivery of Immunomodulatory and Angiogenic Extracellular Vesicles to Enhance Bone Tissue Regeneration." This 3-year project, with a period of performance from Jul 4, 2024 to Aug 31,...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) provides $628,174 to the University of Southern California to conduct research on the cellular origins and molecular mechanisms of arthrofibrosis. The study aims to investigate the role of arginine metabolism and GP130 signaling pathways in promoting fibrotic responses within the joint after injury,...
This $570,878 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research into modulating myofibroblast dynamics to enhance tendon healing following injury. The research aims to define the efficacy of pharmacologically activating the GPR68 receptor to regulate the transition between tenocytes and myofibroblasts during fibrotic tendon healing....