Project Grant R01AI194642
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $527,960 to the Research Institute at Nationwide Children's Hospital on August 18, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a project period extending through July 31, 2030. This Project Grant supports biomedical research investigating the role of glutathione reductase (GSR) in regulating cell metabolism and signaling during neutrophil-pathogen...
- Federal Grant Award Summary Emory University received a $922,840 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 2, 2026, with a completion date of January 31, 2031. The grant funds research on Inducible Hepatic-Associated Lymphoid Tissue (iHALT) generation and maintenance of long-lived plasma cells in response to hepatotropic viral infection. The research utilizes a...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $899,850 to the Whitehead Institute for Biomedical Research under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 20, 2026, for a project concluding January 31, 2031. This Project Grant funds investigator-initiated biomedical research aimed at elucidating the molecular mechanisms by which apicomplexan parasites recognize and invade host cells. The research will...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $659,663 to the Beckman Research Institute of the City of Hope under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 1, 2025, for a five-year project period concluding July 31, 2030. The grant supports fundamental research investigating the role of RNA modification in the development and function of invariant natural killer T (iNKT) cells, specialized...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a $670,881 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct investigator-initiated biomedical research on human granulocytic anaplasmosis (HGA), an emerging infectious disease caused by the bacterium Anaplasma phagocytophilum (APH). The research, which commenced April 1, 2026 and extends through March 31, 2031, focuses on...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $899,741 to the Scripps Research Institute under the Allergy and Infectious Diseases Research program (CFDA 93.855) beginning April 1, 2026, with a completion date of March 31, 2031. This Project Grant funds the development of a long-acting injectable (LAI) therapy for hepatitis B virus (HBV) treatment in individuals co-infected with human immunodeficiency virus (HIV). The research addresses a...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $155,454 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 1, 2025, through July 31, 2027. This award funds research to identify and characterize molecular mechanisms of Venezuelan Equine Encephalitis Virus (VEEV) entry into host cells and to develop enhanced therapeutic interventions targeting...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $615,446 Project Grant to the University of Wisconsin-Madison on April 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The five-year project, concluding March 31, 2031, supports investigator-initiated biomedical research examining novel mechanisms of arterivirus entry, transmission, and persistence in host cells. The research focuses on defining molecular...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Harvard Medical School a Project Grant of $835,269 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 6, 2026, with a completion date of January 31, 2031. This research initiative investigates cytokine regulation of lymphocyte trafficking, specifically examining how high endothelial venules (HEV)—specialized microvessels in secondary lymphoid organs—are formed...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $416,005 Project Grant to the University of California Santa Cruz under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 15, 2025, with a completion date of July 31, 2027. This award funds research to establish the structural and molecular basis for human astrovirus (HAstV) entry into human cells, with the ultimate objective of identifying functional sites on...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $708,193 Project Grant to the Research Institute at Nationwide Children's Hospital under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective May 19, 2026, through April 30, 2031. The award funds basic biomedical research aimed at elucidating the viral entry mechanisms of Hepatitis E Virus (HEV), specifically examining how quasi-enveloped virions (EHEV) enter host cells. This research addresses a critical public health gap, as HEV infection is a significant cause of hepatitis globally with elevated mortality rates in pregnant women, and no HEV-specific treatments currently exist. The research deliverables include investigative studies to determine the fate of the quasi-envelope during EHEV entry and the role of host proteases in HEV infection. Specifically, the project will test hypotheses regarding lysosomal membrane degradation, cholesterol extraction, and proteolytic processing mechanisms required for successful viral capsid exposure and receptor interaction. By generating scientific knowledge of HEV's infectious cycle and entry pathways, the grant aims to advance understanding of disease mechanisms and support the development of future therapeutic interventions for this infectious disease.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $708.2k | 5/20/26 |