Project Grant R03AI194212
Award Date
8/1/25
Completion Date
7/31/27
Dollars Obligated
$155K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Missouri, USA
Similar Awards
This Project Grant award, valued at $792,687.00 and issued by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to define the structural features of sialoglycans necessary for influenza A virus (IAV) infection and adaptation across various host species. The key activities under this award include: 1) using CRISPR/Cas9 techniques to truncate different types of sialoglycans in human lung...
This $769,115 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to advance the understanding of how neurotropic viruses, including flaviviruses and alphaviruses, can directly enter the central nervous system (CNS) through newly described meningeal structures called arachnoid cuff exit (ACE) points. The research team from The Washington University in St. Louis will...
This Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research to evaluate the ferret as an animal model for assessing antiviral efficacy against Venezuelan equine encephalitis virus (VEEV). The $423,500 award to the University of Tennessee Health Science Center will fund studies to: 1) assess the pathogenesis of intranasal VEEV infection in ferrets, and 2) evaluate the...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $254,250 to New York University (NYU) from July 1, 2025 to June 30, 2027. The funding supports research to understand how pathogenic alphaviruses, such as chikungunya virus, infect and spread through human microvascular endothelial cells. The research aims to identify viral and host factors that restrict alphavirus...
This $477,226 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to discover novel antiviral systems in microbial eukaryotes. The research will focus on understanding how the amoeba genus Acanthamoeba defends against giant viruses called Megavirales, and then expand that knowledge to other microbial eukaryotes. The project will leverage cutting-edge AI techniques and...
This $583,047 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand how Rift Valley Fever Virus (RVFV) disseminates from the site of infection in the skin to the central nervous system (CNS). The project aims to establish the routes and mechanisms by which RVFV invades the CNS following peripheral exposure, using novel rodent CNS infection models...
This Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $128,052 to Virginia Polytechnic Institute & State University (Virginia Tech) to investigate the role of the Rift Valley Fever Virus (RVFV) non-structural small (NSS) protein in modulating the host autophagy pathway. The project aims to define the molecular mechanism of the NSS-LC3 interaction and assess its impact...
This Project Grant award, valued at $681,755.00 and issued by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research into the intracellular assembly, maturation, and trafficking of glycoprotein complexes from four rodent-infecting hantaviruses. The research aims to delineate the virus-host interactions required for the proper localization and function of these glycoprotein complexes, which...
This Project Grant award of $536,871 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to identify pan-arenavirus sites of vulnerability through machine learning and artificial neural network molecular screening of small molecules against arenavirus glycoprotein complexes (GPC) and RNA polymerases (RNAP). The proposed research seeks to define molecular specificities and commonalities across...
This Project Grant award, with a total funding amount of $3,161,373.00, was awarded on July 22, 2025 by the National Institute of Allergy and Infectious Diseases (NIAID), which administers the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The award supports research to understand the transmission dynamics and fitness of the reemerging St. Louis Encephalitis Virus (SLEV) in mosquito vectors and avian reservoirs, particularly in the context of the concurrent...