Project Grant R01AG090601
Award Date
1/1/25
Completion Date
12/31/29
Dollars Obligated
$637K
Federal Agency
National Institute on Aging
Awardee
Mayo Clinic (Y2K4F9RPRRG7)
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Rochester, MN 55905, USA
Similar Awards
This $676,000 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to study the impact of the 2016 CDC opioid prescribing guidelines on disparities in opioid utilization among older adults with opioid-responsive pain conditions.
The research will focus on three subgroups of older adults at high risk of pain undertreatment: those with Alzheimer's and related dementias, racial/ethnic minoritized individuals, and those experiencing socioeconomic...
This $357,750 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund research to explore age-related differences in the effects of opioids on locomotion, nociception, and thermoregulation, as well as opioid self-administration in rat models of young-adult and middle-aged populations. The research aims to investigate how the middle-adult developmental stage may influence sensitivity to oxycodone, heroin,...
This federal Project Grant award, valued at $736,503.00 and issued by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), aims to evaluate the effects of combining cognitive-behavioral therapy for insomnia (CBTI) with morning bright light treatment (MBLT) in preventing chronic post-surgical pain (CPSP) and reducing opioid use among older adults undergoing total knee arthroplasty.
The prime awardee, The Johns Hopkins University, will conduct a randomized...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $170,000 to The Spaulding Rehabilitation Hospital Corporation to conduct research aimed at improving chronic pain management. The project will use advanced meta-analytic methods and statistical learning to assess the comparative effects of neuroplasticity-targeted interventions (NTIs) for chronic pain, and develop predictive models to determine optimal NTI treatments. The research involves...
This $205,000 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research at the University of California, San Francisco (UCSF) to investigate the role of "hyperalgesic priming" - a form of neuroplasticity - in contributing to the high incidence of chronic pain in the elderly. The key objectives are to: 1) Establish that aged rats exhibit nociceptor plasticity and determine if it is associated with systemic inflammation, 2) Identify...
The University of Washington was awarded a $1,365,011 Project Grant by the National Institute on Aging (CFDA 93.866 Aging Research) to conduct a study on the mechanisms of mindfulness meditation and self-hypnosis for pain management in older adults with chronic pain. The 5-year study (9/26/2024 - 8/31/2029) aims to use neuroimaging techniques to determine how these non-pharmacological interventions modulate brain function to reduce chronic pain, and to identify patient characteristics that...
This Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) provides $945,966 in funding to Rowan University to conduct research aimed at determining if the GPR83 pathway is a valid target for reducing the abuse liability of opioid medications. The research involves using a combination of biochemistry, neuroanatomy, electrophysiology, and imaging techniques to identify physical and functional interactions between the neuropeptide...
This $779,969 Project Grant awarded by the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to improve perioperative care for patients with opioid use disorder. The grant will fund a multi-year study led by the Regents of the University of Michigan to prospectively capture patient-reported pain and opioid use among individuals with opioid use disorder undergoing common surgical procedures. The research team will also develop and...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $159,711 to the University of California, Los Angeles (UCLA) to conduct research on the electrophysiological dynamics of acute opioid use in human reward, affect, and pain pathways.
The key objectives of this 5-year research project are to: 1) assess changes in reward and affect network connectivity during acute opioid administration, 2)...
The National Institute on Drug Abuse (NIDA) awarded a $701,959 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the Regents of the University of Michigan to improve perioperative care for patients with opioid tolerance. The project aims to prospectively capture patient-reported opioid use and pain outcomes among individuals with opioid tolerance undergoing common surgical procedures, and develop a clinical care pathway to optimize outcomes across a network of...