Project Grant R01AG088324

Award Date 6/1/25
Completion Date 3/31/30
Dollars Obligated $630K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
San Francisco, CA 94158, USA
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This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to The Regents of the University of California, San Francisco (UCSF) provides $1,275,512 in funding over 2 years from June 1, 2025 to May 31, 2027. The objective is to determine how different forms of the protein progranulin (PGRN) impact the accumulation of the TDP-43 protein, which is associated with neurodegenerative diseases like Alzheimer's, frontotemporal dementia, and limbic-predominant...
This three-year, $5.782 million project grant from the National Institute on Aging, part of the Department of Health and Human Services, will support research into single-cell characterization of frontotemporal lobar degeneration caused by mutations in the progranulin gene. The University of California, San Francisco will map the transcriptome and gene regulatory networks that define glial pathology and neuronal vulnerability in the frontal cortex and thalamus of progranulin-deficient...
This $4,893,884 Project Grant from the National Institute on Aging, part of the Department of Health and Human Services, supports research under the Aging Research federal grant program (CFDA 93.866). The University of Florida will lead a collaborative effort to understand the role of central and peripheral immune crosstalk in frontotemporal dementia with progranulin mutations (FTD-GRN), an Alzheimer's disease-related dementia. The University of Florida and sub-awardees the J. David Gladstone...
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