Project Grant R01AA033259
- The National Institute on Alcohol Abuse and Alcoholism awarded Kaiser Foundation Hospitals $759,219 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct early identification research on alcohol-associated liver disease in primary care settings. Kaiser Foundation Hospitals, through its Kaiser Foundation Research Institute division, will recruit 1,300 patients to determine the prevalence of current liver disease using transient elastography across all AUDIT-C...
- The National Institute on Alcohol Abuse and Alcoholism awarded Public Health Institute $1,291,065 under the Alcohol Research Programs (CFDA 93.273) on September 20, 2025. The project conducts analyses of alcohol-related mortality in the United States with emphasis on spirits consumption, examining mortality rate relationships with beverage-specific per capita consumption and policy interventions. The work addresses mortality trends that have increased dramatically since 1999 and particularly...
- The National Institute on Alcohol Abuse and Alcoholism awarded Cedars-Sinai Medical Center $1.235 million under the Alcohol Research Programs (CFDA 93.273) on September 10, 2025, to investigate the role of prohibitin 1 (PHB1) in ethanol's sensitizing effect on colorectal liver metastasis. Research will examine how excessive alcohol intake depletes hepatocyte nuclear and cytosolic PHB1, increasing matrix metalloproteinase-7 (MMP-7) expression and rendering the liver susceptible to colorectal...
- The National Institute on Alcohol Abuse and Alcoholism, part of the Department of Health and Human Services National Institutes of Health, awarded Mayo Clinic $404,352 on September 15, 2025, under the Alcohol Research Programs (CFDA 93.273) to develop machine learning and spatial transcriptomics tools for diagnosis and prognosis of alcohol-associated liver disease (ALD), metabolic dysfunction-associated steatotic liver disease (MASLD), and mixed-etiology metabolic syndrome-associated alcoholic...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Regents of the University of California, San Francisco $613,750 on June 15, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate brain glucose metabolism dysfunction in alcohol use disorder. The research examines how alcohol activates the mTORC1 signaling pathway in dopamine D1 receptor-expressing neurons within the nucleus accumbens, leading to suppression of glycolytic enzymes including aldolase A and...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of Kansas Medical Center Research Institute, Inc. $596,476 on May 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate the role of acute phase response signaling in alcohol-associated liver disease resolution. The project, awarded as a Project Grant (R01AA032810), funds research examining how hepatocytes direct a resolution program following alcohol cessation, producing signals that alter liver...
- The National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health within the Department of Health and Human Services, awarded $682,736 to Beth Israel Deaconess Medical Center, Inc. on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate myeloid-derived suppressor cells (MDSCs) in alcohol-associated steatohepatitis. The award funds research characterizing MDSC phenotypes and immunoregulatory capacity in alcohol-associated hepatitis...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Regents of the University of California, San Francisco $696,490 on July 20, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct the Redefining Optimal Phosphatidylethanol (PETH) Cutoffs for Alcohol Screening (ROCS) study. The project will recruit 900 persons who drink alcohol from a large urban health system's electronic health records to establish evidence-based PETH cutoff values for detecting unhealthy alcohol...
- The National Institute on Alcohol Abuse and Alcoholism awarded Duke University $2,725,992 under the Alcohol Research Programs (CFDA 93.273) on September 1, 2026, to assess the impact of three employer-sponsored strategies on alcohol use disorder (AUD) detection, treatment, and health outcomes among working-age adults with private insurance. The project will evaluate whether expanding clinician provider networks, reducing out-of-pocket financial barriers to care, and implementing...
- The National Institute on Alcohol Abuse and Alcoholism, part of the Department of Health and Human Services National Institutes of Health, awarded $177,551 to The Trustees of Columbia University in the City of New York on July 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to support a K99/R00 Project Grant. The award funds research training and mentorship for Dr. Emilie Bruzelius to investigate how economic stressors mediate prenatal alcohol use and related birth outcomes. In the...
The National Institute on Alcohol Abuse and Alcoholism, a component of the Department of Health and Human Services National Institutes of Health, awarded Kaiser Foundation Hospitals $2,591,645 on August 5, 2026, under the Alcohol Research Programs (CFDA 93.273) to develop and validate risk-prediction models for alcohol-associated liver disease and metabolic dysfunction-associated steatotic liver disease with unhealthy alcohol intake. The recipient will conduct a multi-method study based at Kaiser Permanente Northern California to develop clinical risk-prediction models incorporating clinician and patient perspectives and using characteristics commonly available in electronic health records to identify patients at high risk of developing these conditions. The work includes qualitative interviews with clinicians and patients across primary care, addiction medicine, and gastroenterology/hepatology to identify implementation barriers and facilitators, estimate tolerance ranges for prediction model alerts, and inform predictor selection. The study will use Kaiser Permanente's comprehensive electronic health record data to build and validate predictive models for early identification of at-risk patients with alcohol use disorder, with the objective of facilitating targeted delivery of interventions before severe symptoms emerge. Work is performed in Pleasanton, California, with a period of performance through July 31, 2030. The award is classified as a Project Grant, an assistance type supporting research projects approved for funding by the National Advisory Council on Alcohol Abuse and Alcoholism and selected based on scientific merit, program balance, and relevance to NIAAA priorities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.6m | 8/4/26 |