Project Grant R01AA033041
- The National Institute on Alcohol Abuse and Alcoholism awarded Duke University $191,443 under the Alcohol Research Programs (CFDA 93.273) on May 1, 2026, to conduct a five-year study examining the proximal relationship between alcohol misuse and suicidal thoughts and behaviors among youth, with focus on executive functioning deficits and interpersonal stress as potential mechanisms of risk. The research will enroll 90 youth participants presenting to two emergency departments in Durham, North...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Johns Hopkins University $766,320 on August 10, 2026, under the Alcohol Research Programs (CFDA 93.273) to characterize the health care settings where women with alcohol use disorder receive initial diagnosis and identify missed opportunities for earlier intervention and engagement in treatment. The research assembles diverse data sources from 2016 through 2029, including Medicare, Medicaid, and commercial insurance claims...
- The National Institute on Alcohol Abuse and Alcoholism, part of the Department of Health and Human Services National Institutes of Health, awarded $702,720 to Indiana University Indianapolis on August 10, 2026, under the Alcohol Research Programs (CFDA 93.273) project grant R01AA031671. The award funds research investigating posterior default mode network modulation as a treatment target in alcohol use disorder. The research examines how dysfunction in the medial posterior default mode...
- The National Institute on Alcohol Abuse and Alcoholism awarded New York University School of Medicine $2.920164 million on August 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to develop and evaluate a precision prevention approach for identifying and addressing behavioral health treatment gaps that drive suicide risk. The project will identify subgroups at highest risk of suicidal thoughts and behaviors, characterize which combinations of mental and substance use disorders place...
- Federal Grant Award Summary Wake Forest University Health Sciences received a $2.55 million Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded September 5, 2025, with completion targeted for August 31, 2029. The grant supports research investigating the insula-bed nucleus of the stria terminalis (BNST) neural circuit's role in regulating alcohol use disorder (AUD). The research project focuses on...
- The National Institute on Alcohol Abuse and Alcoholism awarded Kaiser Foundation Hospitals $759,219 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct early identification research on alcohol-associated liver disease in primary care settings. Kaiser Foundation Hospitals, through its Kaiser Foundation Research Institute division, will recruit 1,300 patients to determine the prevalence of current liver disease using transient elastography across all AUDIT-C...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of North Carolina at Chapel Hill $444,576 on May 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to evaluate GLP-1 receptor agonists on alcohol-related behaviors. The recipient will conduct a preclinical screening pipeline assessing how GLP-1 receptor agonist compounds—including semaglutide, tirzepatide, and retatrutide—affect alcohol subjective and interoceptive effects and alcohol reinforcement in the...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Johns Hopkins University $616,371 under the Alcohol Research Programs (CFDA 93.273) on June 10, 2026, to conduct a double-blind randomized controlled trial testing daridorexant, a dual orexin receptor antagonist, for reducing alcohol craving and use and improving total sleep time in patients with alcohol use disorder and co-occurring sleep disturbance. Participants recruited from a residential treatment facility will be...
- The National Institute on Alcohol Abuse and Alcoholism awarded Auburn University $629,828 on September 20, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a multimodal assessment of neural, neuroendocrine, and immune responses to alcohol cues in binge drinkers across laboratory and real-world settings through August 31, 2030. The research examines neurobiological factors—neural activation, cortisol dysregulation, interleukin-6 elevation, and craving responses—as components...
- The National Institute on Alcohol Abuse and Alcoholism awarded RTI International $1,759,221 on September 20, 2025, under the Alcohol Research Programs (CFDA 93.273) to develop small molecule modulators of RXFP3 as therapeutic agents for alcohol use disorder. RTI International will optimize lead-like RXFP3 negative allosteric modulator (NAM) compounds to improve potency and absorption, distribution, metabolism, and excretion/pharmacokinetic properties, then evaluate their effects in animal models...
The National Institute on Alcohol Abuse and Alcoholism awarded Duke University $2,725,992 under the Alcohol Research Programs (CFDA 93.273) on September 1, 2026, to assess the impact of three employer-sponsored strategies on alcohol use disorder (AUD) detection, treatment, and health outcomes among working-age adults with private insurance. The project will evaluate whether expanding clinician provider networks, reducing out-of-pocket financial barriers to care, and implementing income-proportional deductible plans improve AUD care access and outcomes. The research employs a quasi-experimental design using a 17-year longitudinal cohort (2012–2028) of 175 million commercially insured adults from the Health Care Cost Institute database. Specific aims include assessing the impact of transitioning from narrow-network health maintenance organization/point-of-service plans to broad-network preferred provider organization plans on AUD detection, treatment, and acute preventable complications, and evaluating effects of large reductions in out-of-pocket costs on the same outcomes. Duke University's Office of Research Administration serves as the recipient institution. Work is performed in Durham, North Carolina. The period of performance runs from September 1, 2026, through August 31, 2030. The assistance type is a Project Grant, which NIH typically funds for up to five years with potential for renewal.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.7m | 8/24/26 |