Project Grant R01AA032010
Award Date 9/10/25
Completion Date 6/30/30
Dollars Obligated $618K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
California, USA
Similar Awards
- This $177,736 Project Grant award was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) to Beth Israel Deaconess Medical Center, Inc. (Bidmc) located in Massachusetts. The project aims to investigate the role of hepatokines, predominantly hepatocyte-secreted proteins, in the pathogenesis of alcohol-associated liver disease and alcohol-associated hepatitis. Specifically, the research will explore the involvement of the...
- This federal Project Grant award of $3,182,397.00 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) to the University of California, San Diego (UCSD). The grant aims to characterize the role of host gut proteases, particularly cathepsin B, and the immune response in alcohol-associated liver disease (ALD) in both a human cohort and a mouse model. The research seeks to determine how alcohol-mediated induction of...
- This federal Project Grant award of $227,844.00 from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 Alcohol Research Programs) supports research to elucidate the impact of chronic and excessive alcohol consumption on tumor suppressor genes and their role in the development of alcohol-related liver cancer. The project aims to use both candidate and systemic approaches to identify and characterize key tumor suppressor genes crucial in the pathogenesis of alcohol-related...
- This federal Project Grant award of $701,051 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273). The grant supports research to investigate the phenotypes and functions of distinct neutrophil populations in patients with severe alcohol-associated hepatitis (AH). Key objectives include: 1) Characterizing the transcriptomic profiles and functional roles of neutrophil subsets in AH using single-cell RNA sequencing; 2)...
- This federal Project Grant award of $659,865 from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) supports research at Yale University to investigate the role of aberrant mitochondrial calcium signaling in the development of alcohol-associated hepatitis (AAH). The project will examine how the expression and localization of the inositol trisphosphate receptor (ITPR) isoforms, particularly ITPR3, impact mitochondrial calcium signals and cellular...
- This federal Project Grant award of $560,567, provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), will fund a research project titled "Increasing Spirits Use and Alcohol-Related Mortality in the US: Analyses of Mortality Rate Relationships with Beverage-Specific Per Capita Consumption and Policies." The project aims to analyze the recent trends in alcohol-related mortality in the U.S., with a focus on the link...
- The University of California Irvine was awarded a $412,125 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program. The grant funds a research project to comprehensively determine how alcohol consumption alters the metabolism of critical organs, which can contribute to alcohol-induced organ damage. The project will employ arteriovenous metabolomics to quantitatively measure the dynamic metabolic...
- This Project Grant award of $477,626 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program. The purpose of the award is to investigate the role of the TET1 enzyme in regulating sex differences in alcohol-associated liver tumorigenesis. The award supports a research project at Tulane University exploring how TET1 affects the development of alcohol-associated liver disease, particularly in female mice....
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $404,250 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Tennessee Health Science Center. The grant, awarded on September 23, 2025 with an ultimate completion date of August 31, 2027, supports research to explore the role of margaric acid in alcohol-associated liver diseases (AALD). The project aims to determine if margaric acid supplementation can attenuate alcohol-induced gut and liver...
- This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), provides $249,000.00 to East Tennessee State University to characterize acetaldehyde-protein adducts and their effects on lymphocyte function in alcohol-associated liver disease. The research aims to investigate how the ethanol metabolite acetaldehyde forms adducts on proteins, particularly albumin, and how this modulates the pathogenesis of...