Project Grant R01AA031800
- Federal Project Grant Award Summary Louisiana State University received a $1,192,109 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective August 15, 2025, with completion anticipated April 30, 2030. The award supports basic neuroscience research aimed at elucidating the epigenetic mechanisms underlying stress-potentiated ethanol drinking and alcohol use disorder (AUD). The research investigates the...
- Federal Grant Award Summary Louisiana State University Health Sciences Center New Orleans received a $1.0125 million Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded September 5, 2025, with a completion date of May 31, 2030. The grant supports basic neuroscience research investigating the molecular mechanisms linking social stress to alcohol use disorder (AUD). Specifically, the research examines how...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Louisiana State University Health Sciences Center New Orleans a Project Grant totaling $1,269,659 under the Alcohol Research Programs (CFDA 93.273), effective September 25, 2025, through August 31, 2030. This award funds research to develop geroprotective precision medicine strategies targeting people with HIV (PWH) who use alcohol, addressing the critical gap in evidence-based treatments for...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded The Medical University of South Carolina $459,707 on September 5, 2025, under the Alcohol Research Programs (CFDA 93.273) to support a five-year research project extending through May 31, 2030. This Project Grant funds basic neuroscience research investigating the physiological mechanisms underlying alcohol use disorder (AUD), specifically examining how chronic intermittent ethanol (CIE)...
- Federal Grant Award Summary Funding Agency: National Institute on Alcohol Abuse and Alcoholism (NIAAA) Federal Grant Program: Alcohol Research Programs (CFDA 93.273) Award Amount: $559,180 Award Date: September 1, 2025 Project Period: September 1, 2025 – June 30, 2030 Awardee: RTI International (Research Triangle Institute), Research Triangle Park, North Carolina RTI International will conduct multi-omic research to identify neurobiological factors underlying alcohol use disorder (AUD) with...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Florida a $560,108 Project Grant on September 15, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a five-year investigation into the neurocognitive mechanisms of resilience to alcohol use disorder (AUD). The research will examine how attentional ability protects against AUD development in at-risk young adults with a family history of alcohol use disorder. This...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Boston University Medical Campus a $580,556 Project Grant, effective May 1, 2026 through January 31, 2031, under the Alcohol Research Programs (CFDA 93.273). This award supports translational and mechanistic research investigating the role of pituitary adenylate cyclase activating polypeptide (PACAP) in heavy alcohol drinking and associated anxiety-like behaviors. The research employs...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Tennessee Health Science Center a Project Grant totaling $399,076 (awarded September 15, 2025; completion date August 31, 2027) under the Alcohol Research Programs (CFDA 93.273). The project focuses on developing a rapid screening platform for identifying and repurposing FDA-approved drugs to treat alcohol use disorder (AUD) and address chronic alcohol tolerance. Using the...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $459,343 Project Grant to the University of Pittsburgh under the Alcohol Research Programs (CFDA 93.273) to conduct fundamental neuroscience research examining the mechanisms through which alcohol affects prefrontal cortex circuits, with performance extending from September 20, 2025 through July 31, 2030. The research focuses on understanding how vasoactive intestinal peptide-expressing...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Mayo Clinic a $734,283 Project Grant effective September 5, 2025, through June 30, 2030, under the Alcohol Research Programs (CFDA 93.273) to investigate the neurobiological mechanisms underlying alcohol use disorder (AUD) and treatment response. The primary research deliverable involves measuring circulating neuroactive steroid levels—specifically allopregnanolone (ALLO), its precursors, and...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $321,929 Project Grant to Louisiana State University Health Sciences Center-Shreveport on May 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct a five-year research project extending through January 31, 2031. The research delivers scientific investigation into the neurobiological mechanisms underlying alcohol tolerance and alcohol use disorder (AUD), specifically examining the role of neurogranin (NG) and nitric oxide (NO) regulation in the medial prefrontal cortex (mPFC). The awardee will utilize operant conditioning models, behavioral testing, microdialysis, and label-free proteomics to elucidate how NG levels regulate alcohol tolerance development across genetically modified mouse models, including MPFC-specific NG knockout and overexpression variants, with the ultimate goal of identifying targeted treatment mechanisms for the estimated 14.4 million U.S. adults suffering from AUD. The research deliverables encompass two primary investigative aims: mechanistic analysis of how chronic alcohol reduces NG expression in the mouse mPFC, coupled with behavioral evaluation of alcohol tolerance development in transgenic mouse models; and examination of alcohol tolerance effects in inducible NG knockout mice within excitatory neurons. These scientific products will contribute fundamental knowledge to the Alcohol Research Programs' mission of developing improved treatment methods and prevention strategies for alcoholism and alcohol-related disorders through rigorous preclinical investigation.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $321.9k | 5/1/26 |