Project Grant R01AA031732
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Pennsylvania a Project Grant of $115,307 under the Alcohol Research Programs (CFDA 93.273) for the period September 1, 2025, through August 31, 2027. This K99/R00 career development award supports research examining the neuropharmacological effects of the ketogenic diet (KD) on alcohol intoxication in both healthy individuals and those with alcohol use disorder (AUD). The research...
- Federal Grant Award Summary Emory University received a $755,539 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded September 10, 2025, with completion by May 31, 2030. This research project generates real-world evidence on the utilization, effectiveness, and safety of glucagon-like peptide-1 receptor agonists (GLP-1RAs) for treating alcohol use disorder (AUD). Using administrative claims data and linked...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $459,343 Project Grant to the University of Pittsburgh under the Alcohol Research Programs (CFDA 93.273) to conduct fundamental neuroscience research examining the mechanisms through which alcohol affects prefrontal cortex circuits, with performance extending from September 20, 2025 through July 31, 2030. The research focuses on understanding how vasoactive intestinal peptide-expressing...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Boston University Medical Campus a $580,556 Project Grant, effective May 1, 2026 through January 31, 2031, under the Alcohol Research Programs (CFDA 93.273). This award supports translational and mechanistic research investigating the role of pituitary adenylate cyclase activating polypeptide (PACAP) in heavy alcohol drinking and associated anxiety-like behaviors. The research employs...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $444,576 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) to evaluate the efficacy of glucagon-like peptide-1 receptor agonist (GLP-1RA) compounds and related medications in reducing alcohol use disorder (AUD). The award, effective May 1, 2026, through January 31, 2031, supports a preclinical screening pipeline designed to...
- Federal Project Grant Award Summary Louisiana State University received a $1,192,109 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective August 15, 2025, with completion anticipated April 30, 2030. The award supports basic neuroscience research aimed at elucidating the epigenetic mechanisms underlying stress-potentiated ethanol drinking and alcohol use disorder (AUD). The research investigates the...
- Federal Grant Award Summary Wake Forest University Health Sciences received a $2.55 million Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective September 5, 2025, with a completion date of August 31, 2029. The award supports a four-year research initiative investigating the insula-bed nucleus of the stria terminalis (BNST) neural circuit's role in alcohol use disorder (AUD) development. The...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $157,040 to the Regents of the University of Minnesota on March 9, 2026, under the Alcohol Research Programs (CFDA 93.273) to support neuroscience research investigating the neural mechanisms underlying aversion-resistant alcohol drinking (ARD). The research project, with an estimated completion date of January 30, 2028, employs optogenetics and simultaneous in-vivo electrophysiology to...
- Federal Project Grant Award Summary Wake Forest University Health Sciences received a $647,330 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded on September 12, 2025, with an ultimate completion date of July 31, 2030. The grant funds a longitudinal research initiative examining epigenetic profiles in the alcohol-naive primate cortex to identify biological risk factors predisposing individuals to alcohol...
- Federal Grant Award Summary The University of Pennsylvania received a $569,223 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective August 1, 2025, through July 31, 2030. This research project examines the efficacy and tolerability of ketone supplement (KS) drinks in reducing alcohol craving and consumption among individuals with Alcohol Use Disorder (AUD). The research investigates two primary...
Drexel University received a $564,306 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) effective May 1, 2026 through January 31, 2031. The award supports research investigating the suppression of ethanol dependence-induced maladaptive behavioral and consumption patterns through modulation of the glucagon-like peptide-1 (GLP-1) system. The research employs a chronic intermittent ethanol exposure model to examine how GLP-1 receptor activity in discrete central nervous system circuits—specifically the prefrontal cortex and paraventricular nucleus of the thalamus—can reduce binge-like eating and ethanol drinking behaviors, as well as relapse behaviors during alcohol withdrawal. The project delivers preclinical research findings and mechanistic insights applicable to development of improved pharmacological treatment strategies for alcohol use disorder. By identifying specific forebrain GLP-1 receptor targets, the research aims to provide a scientific foundation for reducing off-target side effects associated with existing GLP-1 receptor agonist medications while maintaining their therapeutic efficacy in suppressing aberrant food and alcohol consumption. This mechanistic investigation contributes to the NIAAA's broader mission of developing improved treatment methods and prevention strategies for alcoholism and alcohol-related problems.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $564.3k | 5/5/26 |