Project Grant R00HD113880
- This Project Grant award of $448,182 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to develop a novel physiologically based pharmacokinetic (PBPK) modeling approach to improve predictions of drug transfer into breast milk. The research seeks to address the significant safety concerns around medication use by breastfeeding women, as studies show they use...
- This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $154,796 to the Massachusetts Institute of Technology (MIT) to develop a biomimetic lactating mammary lobe system. The objective is to create an in vitro model that faithfully mirrors breast milk synthesis processes and can be used as a screening testbed to evaluate the safety of drugs and...
- The Project Grant award of $632,928 from the National Institute of Child Health and Human Development's (NICHD) Child Health and Human Development Extramural Research program (CFDA 93.865) supports a research study on the neurodevelopmental, health, and economic outcomes of former very preterm infants randomized to an economic intervention supporting mother's own milk. The award, provided to Rush University Medical Center, will fund the comprehensive research initiative from September 2025...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $167,400.00 to Brigham & Women's Hospital Inc. to conduct research on the effects of maternal micronutrient supplementation during lactation on infant neurodevelopment. The key objectives are to: 1) Determine if maternal multiple micronutrient supplementation during lactation...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $519,054 in funding to Loyola University of Chicago for a randomized controlled trial investigating the use of multisensory early oral administration of human milk (M-MILK) to enhance stress regulation, neurodevelopment, and oral feeding skills in very preterm infants. The...
- The National Institute of Child Health and Human Development (NICHD), part of the U.S. Department of Health and Human Services, awarded a $655,674 Project Grant to the University of Colorado-Denver under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant, awarded on July 24, 2025, will support research investigating the role of lipid droplet docking in lactation initiation and milk secretion. The proposed studies use mouse models, imaging techniques,...
- The National Institute of Child Health and Human Development (NICHD) awarded a $657,909 Project Grant under the Child Health and Human Development Extramural Research (CFDA 93.865) program to the Joslin Diabetes Center, Inc. in Boston, Massachusetts. The grant funds a research project to systematically investigate the effects of maternal exercise during lactation on the composition of human breast milk and the subsequent metabolic impacts on infants. The research aims to measure changes in...
- This $161,892 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research comparing the microbiome and human milk oligosaccharide composition of preterm infants' own mother's milk versus donor human milk. The study aims to evaluate how these differences relate to the preterm infant gut microbiome and growth outcomes from birth to 36...
- This $768,256 Project Grant awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to conduct a randomized controlled trial to reduce postpartum smoking relapse by promoting breastfeeding. The grant will enroll 280 pregnant mothers who successfully quit smoking during pregnancy, randomizing them into either a breastfeeding intervention group or an attention control group. The...
- The University of Southern California was awarded a $747,000 Project Grant under the Child Health and Human Development Extramural Research (CFDA 93.865) program by the National Institute of Child Health and Human Development. The 3-year grant, running from August 1, 2025 to July 31, 2028, will fund research to: Identify genetic variants influencing human milk composition and the connections between milk metabolomics and the infant gut microbiome. Assess the impact of human cytomegalovirus...
This Project Grant award of $747,000.00 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to evaluate breast pumping protocols and elucidate the molecular and cellular mechanisms underlying enhanced milk production. The research aims to address critical issues around suboptimal breastfeeding practices, which result in significant public health consequences. The study will employ a randomized clinical trial design combined with molecular analyses of mammary gland function and milk composition. Specifically, it will investigate the impacts of different breast pumping regimens on maternal milk production, as well as the associated transcriptomic changes in the mammary gland. Participants will provide milk and blood samples, detailed records of expressed milk volume, and daily questionnaire data. This comprehensive research approach seeks to improve understanding of the physiological mechanisms underlying issues like insufficient milk production, which negatively impact infant growth, maternal health, and overall breastfeeding experiences. The award has a project period from September 15, 2025 to August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $747.0k | 9/9/25 |