Project Grant R00HD105973
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- This Project Grant award, valued at $643,049.00, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports the development of a physiomimetic model of endometrioma, a type of endometriotic lesion, to study processes driving lesion initiation, ovarian stroma invasion, and persistence in a chronic inflammatory environment. The research aims to uncover...
- The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
- This federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), is supporting research on the role of decidual extracellular vesicles in mediating placental insufficiency. The $654,671 award, which commenced on August 1, 2025 and is scheduled for completion by April 30, 2030, is being conducted by the awardee, Yale University. The key...
- This $429,000 federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the gene and environmental influences on placental angiogenesis and severe fetal growth restriction. The University of Colorado-Denver, the awardee organization, will leverage induced pluripotent stem cell technology to better...
- The U.S. National Institute of Child Health and Human Development (NICHD) awarded a $766,982 Project Grant to Carnegie Mellon University under the Child Health and Human Development Extramural Research program (CFDA 93.865). The project aims to develop and validate a novel computational framework to simulate uteroplacental hemodynamics and placentation, with the goal of identifying metrics for early detection of pregnancy complications related to abnormal placental formation. This research...
- The University of California, San Diego (UCSD) received a $151,040 Project Grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant, awarded on January 25, 2026, with a completion date of July 31, 2027, supports research to investigate the effects of rare damaging mutations in TGFβ latent complex proteins found in preeclamptic placentas. The key...
- This federal Project Grant award for $378,123 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to identify and test mechanisms that establish transcriptional regulatory potency in early embryos. The primary activities include using genomic methods like PRO-seq, DREG, and OMNI-ATAC to characterize transcriptionally active regulatory elements, DNA accessibility, and...
- The federal Project Grant award of $429,000 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to characterize placental extracellular vesicles (EVs) throughout human pregnancy. The goal is to develop novel methods to image, count, isolate, and validate placental cell- and size-specific EVs from maternal blood, in order to monitor placental...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $249,000.00 to The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania, to enhance personalized insights into common obstetric disorders using longitudinal deep-phenotyping data. The project aims to compile a...
This Project Grant award of $249,000 was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Connecticut Health Center (UCHC). The funding will support a 3-year research project to study the transcriptional regulation and intercellular signaling at the maternal-fetal interface, with the goal of developing a prognostic model to relate individual transcriptional profiles of endometrial cells to invasion-related maternal-fetal diseases such as preeclampsia, fetal growth restriction, and placenta previa. The project will leverage machine learning, statistical modeling, comparative genomics, and computational regulatory element prediction to prioritize key transcriptional regulatory elements underlying tissue integrity in the endometrium during placental invasion.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.0k | 9/2/25 |