This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, will fund research to define the urinary, biliary, and fecal excretion of per- and polyfluoroalkyl substances (PFAS) and the impact of dietary fiber. The $157,437 award, with a project period from May 10, 2025 to May 9, 2027, will support experiments using humanized PPARA mice to test the hypotheses that biliary excretion of PFAS is...
This federal Project Grant award of $695,853 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research on the impact of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on children's development. The award will fund a collaborative effort between the Arkansas Children's Research Institute, Emory University, and the University of Kentucky Research Foundation to investigate how prenatal PFAS exposure...
This $546,350 Project Grant, awarded on January 13, 2025 by the National Institute of Environmental Health Sciences (CFDA 93.113 Environmental Health), supports research to define the neurotoxic and neurodevelopmental health risks of per- and polyfluoroalkyl substances (PFAS). The primary awardee, The Research Foundation for the State University of New York, will utilize zebrafish models to investigate PFAS uptake mechanisms, cellular impacts, and effects on neurodevelopment and behavior. A...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $260,993 Project Grant (CFDA 93.113 - Environmental Health) to Framergy Inc., in collaboration with Texas A&M University, to develop a novel at-home test kit for the detection of per- and polyfluoroalkyl substances (PFAS) in drinking water. The project leverages the unique properties of metal-organic frameworks (MOFs) and a readily available oxidant to achieve mineralization of PFAS into fluoride ions, which can then...
The University of Southern California was awarded a $1,632,022 Project Grant under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) to develop problem-based, solution-oriented scientific knowledge and innovative technologies to address the issue of per- and polyfluoroalkyl substances (PFAS) water contamination in Superfund and other sites. The 5-year grant, awarded on April 24, 2025, will fund four highly interactive research projects that integrate...
This Project Grant award, totaling $385,219.00, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program. The award supports research to investigate the role of albumin and other serum factors in the accumulation and toxicity of per- and polyfluoroalkyl substances (PFAS) in the body. The key objectives of this 5-year award (ending February 2030) are to: 1) determine whether albumin is a key factor for...
This Project Grant award of $412,000 from the National Science Foundation (NSF) Engineering program (CFDA 47.041) will be used by the University of Massachusetts (UMass) to investigate the use of engineered polymer microparticles to adsorb and remove per- and polyfluoroalkyl substances (PFAS) from wastewater. The central hypothesis is that the adsorption of PFAS molecules will alter the interfacial properties of the microparticles, causing emulsions to destabilize and allowing for the capture...
The National Institute of Environmental Health Sciences (NIEHS) awarded Wayne State University a 3-year, $1,644,161 Project Grant under the Environmental Health program (CFDA 93.113) to study the effects of per- and polyfluoroalkyl substances (PFAS) on atherosclerosis and cholesterol metabolism. The project aims to determine if PFAS mixtures accelerate atherosclerosis in a mouse model, assess how PFAS disrupts bile acid reuptake and leads to increased cholesterol levels, and evaluate the...
This $322,328 Project Grant, awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program, supports research on the occurrence and health impacts of per- and polyfluoroalkyl substances (PFAS) exposure among U.S. volunteer firefighters. The two key objectives are to: (1) assess the prevalence, predictors, and exposure sources of PFAS among volunteer firefighters, and (2) examine associations between PFAS levels and...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $474,639 to North Carolina State University (NC State) to conduct research on estimating the health effects of per- and polyfluoroalkyl substances (PFAS) mixtures. The project aims to develop innovative spatial and tensor-based statistical methods to overcome key challenges in observational PFAS studies, including spatial...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $499,454.23 Project Grant under the Environmental Health (CFDA 93.113) federal grant program to the University of Massachusetts. The grant, entitled "Development of Edible Sorbent Therapies to Mitigate Dietary Exposures to Per- and Polyfluoroalkyl Substances (PFAS)", aims to develop edible, multicomponent sorbents that can effectively reduce PFAS exposures from the diet. The 3-year project will conduct in vitro, in silico, and in vivo studies to characterize PFAS adsorption by processed and nutrient-amended clays, validate detoxification efficacy, and evaluate the safety and efficacy of selected sorbents in animal models. The goal is to establish therapeutic sorbent interventions that can protect vulnerable populations from PFAS exposures during emergencies.