Project Grant R01ES034407
- Federal Project Grant Summary Michigan State University received a $100,000 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective September 27, 2025, with a completion date of August 31, 2027. The award funds research investigating the role of the epicardium and inositol-requiring enzyme 1A (IRE1A) in mediating the effects of environmental chemical exposures on cardiac function. The research...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Southern California a Project Grant of $1.256 million under the Environmental Health program (CFDA 93.113) on April 10, 2026, for a translational research initiative examining per- and polyfluoroalkyl substances (PFAS) and metabolic diseases. The grant supports an eight-year research program (through March 31, 2034) organized into four interconnected research areas:...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Massachusetts Lowell $157,437 under the Environmental Health program (CFDA 93.113) on May 10, 2025, for a two-year project concluding May 9, 2027. This Project Grant supports research defining the urinary, biliary, and fecal excretion pathways of diverse per- and polyfluoroalkyl substances (PFAS) and investigating the impact of dietary fiber on PFAS elimination. The research...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $163,856 Project Grant to the University of New England on April 10, 2026, under the Environmental Health program (CFDA 93.113). This award supports a prospective epidemiological study investigating the association between per- and polyfluoroalkyl substance (PFAS) mixtures and adverse pregnancy outcomes in a cohort of reproductive-aged Black women from Detroit, Michigan. The research...
- Grant Award Summary The University of Michigan received a $771,168 Project Grant award, effective April 1, 2026, through the National Institute of Environmental Health Sciences (NIEHS) Environmental Health program (CFDA 93.113) to conduct a five-year research initiative examining the interplay between per- and polyfluoroalkyl substances (PFAS) and T cell epigenetics in autoimmunity and lupus. The research leverages two complementary population-based cohorts—the Michigan Lupus Epidemiology...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded Brown University a $463,850 Project Grant on September 10, 2025, under the Environmental Health program (CFDA 93.113) to investigate the long-term health effects of prenatal per- and polyfluoroalkyl substances (PFAS) exposure. The primary deliverable is a longitudinal epidemiological study utilizing the New England Family Study (NEFS) cohort to determine whether prenatal PFAS mixture...
- Federal Project Grant Award Summary Duke University received a $3.12M Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded September 5, 2025, with completion targeted for September 4, 2029. The research initiative investigates the mechanisms by which per- and polyfluoroalkyl substances (PFAS) exposure impairs placental function and fetal development through disruption of mitochondrial function and...
- Federal Grant Award Summary Wayne State University received a $1.39 million Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded June 3, 2025, with completion targeted for March 31, 2030. This award supports research investigating how polyethoxylated surfactants—emerging environmental contaminants widely used in consumer products including detergents, cleaners, paints, and pesticides—disrupt metabolic...
- Federal Grant Award Summary Brown University received a $656,250 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective August 6, 2025, through May 31, 2029. This research project will investigate the relationship between prenatal per- and polyfluoroalkyl substances (PFAS) exposure and adult cardiometabolic disease using the New England Family Study (NEFS), a unique prospective cohort that...
- Federal Grant Award Summary Wayne State University received a $143,331 Project Grant from the National Institute of Environmental Health Sciences under the Environmental Health program (CFDA 93.113), awarded September 1, 2025, with completion targeted for March 31, 2026. The grant supports research investigating the molecular mechanisms by which per- and polyfluoroalkyl substances (PFAS) exposure affects male reproductive health, specifically examining impacts on spermatogenesis and sperm...
The National Institute of Environmental Health Sciences (NIEHS) awarded Wayne State University a 3-year, $1,644,161 Project Grant under the Environmental Health program (CFDA 93.113) to study the effects of per- and polyfluoroalkyl substances (PFAS) on atherosclerosis and cholesterol metabolism. The project aims to determine if PFAS mixtures accelerate atherosclerosis in a mouse model, assess how PFAS disrupts bile acid reuptake and leads to increased cholesterol levels, and evaluate the relationship between PFAS exposure and circulating bile acids in a human cohort. The research includes sub-awards to Henry Ford Health System, which will lead epidemiological aspects and statistical analysis for the human cohort study. The overall goal is to better understand the cardiovascular health impacts of widespread PFAS exposure.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.6m | 9/18/23 |