Project Grant P30DA063727
- The National Institute on Drug Abuse awarded The Regents of The University of Colorado, doing business as University of Colorado-Denver, $165,656 on January 6, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279). The award funds basic research investigating dopaminergic modulation of NMDA receptor signaling in the nucleus accumbens, using ex vivo slice electrophysiology combined with optogenetics and iontophoresis in transgenic mouse lines. The research examines how dopamine...
- The National Institute on Drug Abuse awarded $709,085 to The Regents of the University of Colorado, doing business as University of Colorado-Denver, on April 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279). The award funds an implementation trial testing in-hospital opioid treatment program (OTP) intakes to facilitate linkage from hospitalization to outpatient methadone treatment among patients with opioid use disorder. The study uses a staircase cluster randomized...
- The National Institute on Drug Abuse awarded Carnegie Mellon University $217,672 on August 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to measure how addiction-associated genetic variants regulate gene expression across specific brain regions in response to opioids and cocaine. The research measures regulatory activity of candidate human addiction-associated genetic enhancers in the striatum, cortex, hippocampus, and amygdala of mice using in vivo massively parallel...
- The National Institute on Drug Abuse awarded the University of California, San Diego $169,832 on September 30, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to support research into the genetic basis of addiction-related behaviors. The project uses long-read sequencing technology to discover and characterize tandem repeats and structural variants in the genomes of N/NIH Heterogeneous Stock rats, genetic variants that conventional genome-wide association studies overlook....
- The National Institute on Drug Abuse awarded the University of California, San Diego $2,543,114 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to establish the Polysubstance Addiction Research Center, a five-year research initiative addressing polysubstance use disorders through integrated behavioral, molecular, circuit, and immunometabolic investigation. The center will conduct three primary research projects: brain connectomic analysis, brain...
- The National Institute on Drug Abuse awarded Boston Children's Hospital $800,131 on May 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate the functions and mechanisms of a molecularly defined prefrontal cortex neuron subtype in drug addiction. The research focuses on identifying and characterizing POU3F1-expressing layer 5 neurons in the prefrontal cortex and their role in regulating cocaine-seeking behavior. The work employs single-cell RNA sequencing...
- The National Institute on Drug Abuse awarded The Regents of the University of Colorado, doing business as University of Colorado-Denver, $496,402 on April 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) for a two-year project grant (R21DA065027) running through March 31, 2028. The award funds rigorous assessment of cannabis detection technologies to address impaired driving and public safety concerns. The research compares the performance of two breath-sampling devices...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA), under its Drug Use and Addiction Research Programs (CFDA 93.279), awarded $877,500 to the University of California, San Diego for a two-year project (July 15, 2025 through June 30, 2027) investigating neurobiological mechanisms underlying cocaine use disorder (CUD) susceptibility. The project employs a novel polygenic prediction methodology called RATTACA to identify pre-existing cellular differences in gabaergic and...
- Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a Project Grant of $385,638 to The Regents of the University of Colorado (University of Colorado-Denver) under the Drug Use and Addiction Research Programs (CFDA 93.279) on September 1, 2025, with a completion date of August 31, 2028. This research award funds a three-year neurobehavioral investigation titled "Cannabinoid Tolerance Across Neurodevelopment: Disruption of Value-Driven Behavior and Prevention Through...
- The National Institute on Drug Abuse awarded the Regents of the University of Minnesota $716,254 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a global network study of population, family, and longitudinal human genetic research on tobacco and alcohol use. The award funds research integrating 9 million individuals of global ancestries across a worldwide consortium to identify genetic loci associated with nicotine and alcohol use disorder. The...
The National Institute on Drug Abuse awarded The Regents of the University of Colorado, doing business as University of Colorado-Denver, $1.266 million on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to establish and operate the NIDA Center of Excellence in Omics, Systems Genetics, and the Addictome. The center delivers training, data resources, and analytical tools enabling substance use disorder researchers to integrate data science, quantitative genetics, and artificial intelligence techniques into their work. Core activities include building a collaborative community of NIDA genetics researchers, developing public omics datasets, and creating user-friendly advanced analysis tools. The Systems Analytics and Modeling Research Support Core develops an internship program for undergraduate students interested in data science and addiction research, and creates brain-region-specific proteomics datasets in a panel of inbred rat strains to support translational research linking genetic, molecular, and cellular traits to SUD-related behaviors in rodent models and human clinical prevention and treatment applications. The award runs through May 31, 2031, with place of performance in Aurora, Colorado. This is a Project Grant (assistance type) under the Drug Use and Addiction Research Programs, which supports basic, clinical, translational, and implementation research to develop prevention, diagnosis, and treatment approaches for drug use, misuse, addiction, and overdose.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.3m | 8/24/26 |