Project Grant P30AG103094
- The National Institute on Aging, part of the National Institutes of Health, awarded $1,250,191 to the University of North Carolina at Chapel Hill on February 15, 2026, under the Aging Research program (CFDA 93.866) to develop an integrated artificial intelligence and experimental workflow for accelerating discovery of small-molecule modulators that influence Alzheimer's disease through microglial phagocytosis regulation. The funded work combines AI-driven computational methods with...
- The National Institute on Aging awarded The Leland Stanford Junior University $4.891 million on August 15, 2026, under the Aging Research program (CFDA 93.866) to establish the Stanford University Artificial Intelligence and Technology Collaboratory (SU-AITC) Center for Precision Health & Interventions in Aging and AD/ADRD. The award funds the development and deployment of artificial intelligence algorithms, scalable digital biomarkers, and cost-effective digital interventions to translate...
- The National Institute on Aging awarded a cooperative agreement totaling $1.883 million to Yale University on September 1, 2026, to establish an AI-Powered Coordinating Center for the Artificial Intelligence and Technology Collaboratory (AITC) Program on Aging and Alzheimer's Disease and Related Dementias research under the Aging Research program (CFDA 93.866). Yale will serve as the national hub for the AITC Program, embedding AI throughout administration, research commercialization, and...
- The National Institute on Aging awarded Duke University $1.597 million on September 15, 2025, under the Aging Research program (CFDA 93.866) to support research on epitranscriptomic regulation of microglia in Alzheimer's disease. The research investigates how m6a methylation of adenosine residues in messenger RNA regulates microglial cell function and transitions between resting and activated states during Alzheimer's disease pathogenesis, with the goal of identifying novel...
- The National Institute on Aging, under the Department of Health and Human Services, awarded Duke University $627,830 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop a portable diagnostic system for Alzheimer's disease detection using circulating microRNA biomarkers. Duke's project, titled ADMIRE (Alzheimer's Detection via miRNA Evaluation), integrates two technologies: an amplification-free microRNA biosensing modality called the Inverse Molecular Sentinel and a...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded the University of Notre Dame $582,492 on September 1, 2026, under the Aging Research program (CFDA 93.866) for Project Grant R61AG104103, OPENCARE: Open-Source Infrastructure for Evaluating Conversational AI in Dementia Care. The recipient will develop and deliver two open-source research infrastructures to address the absence of technical evaluation standards for conversational AI in Alzheimer's...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded Duke University $493,972 on January 1, 2026, under the Aging Research program (CFDA 93.866) to investigate cell type-specific epitranscriptomic regulation in the brain during aging and Alzheimer's disease. The research will determine how age-dependent differential methylation of adenosine (M6A) in distinct brain cell types influences the expression of genes associated with Alzheimer's disease. The...
- Federal Grant Award Summary Duke University's Office of Research Administration received a $426,555 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective September 1, 2025, through August 31, 2027. The award supports the development and technical evaluation of CASCADE AMPLIFICATION BY RECYCLING TRIGGER PROBE (CARTP), a novel molecular diagnostic technology designed to enable rapid, multiplex, and ultra-sensitive detection of circulating...
- The National Institute on Aging awarded The Leland Stanford Junior University $630,031 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop an artificial intelligence-driven metabolic clock for distinguishing healthy aging from Alzheimer's disease and Alzheimer's disease-related dementias. The project uses large-scale untargeted metabolomics to identify metabolic deviations associated with cognitive decline in aging and dementia. The research tests the hypothesis...
- The National Institute on Aging awarded Carevirtue Technologies, Inc. $1.717 million on September 20, 2025, under the Aging Research program (CFDA 93.866) to develop an AI-enabled dementia care agent for rural Alzheimer's disease and related dementia (ADRD) care partners. Carevirtue will develop a 24/7 AI-enabled dementia care agent that integrates vetted ADRD caregiving education and support content from the National Institute on Aging, AgeUcate, and other authoritative sources into a large...
The National Institute on Aging awarded Duke University $4.899 million on August 15, 2026, under the Aging Research program (CFDA 93.866) to establish the Duke Artificial Intelligence and Technology Collaboratory for Aging: Governance and Evaluation (DUKE AITC-AIGE), a national initiative bridging the implementation gap between artificial intelligence research and its application in care for older adults and individuals with Alzheimer's disease and related dementias. The collaboratory operates through three integrated cores. The Administrative Core provides national leadership and ethical oversight, manages a national pilot project competition, and liaises with the AITC Coordinating Center to ensure national synergy. The Research Innovation Core serves as a discovery engine by funding and mentoring interdisciplinary pilot projects. The Clinical Implementation and Data Science Core offers specialized consultation for translation and applies the Dynamic Data Reliability framework to quantify data fitness-for-use and ensure datasets are AI-ready. A central methodological innovation is the Trustworthy AI Implementation and Governance (TRIG) Framework, which operationalizes fairness, accountability, and transparency into reproducible methods mandatory for all projects. TRIG requires concrete actions including fairness audits, continuous monitoring for performance drift, and transparent documentation via model cards. The initiative addresses five critical barriers: lack of stakeholder input in problem definition, data limitations in training data, inadequate validation of subgroup performance, insufficient monitoring for model drift, and unaccountable governance. The award period runs through July 31, 2031, with place of performance in Durham, North Carolina.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $4.9m | 8/12/26 |