This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $1,230,000.00 to the Regents of the University of California, San Francisco (UCSF) from Aug 15, 2024 to May 31, 2029. The goal is to leverage technology to facilitate memory and cognitive function in older adults, particularly those at risk of Alzheimer's disease and related dementias. The award will support a Behavioral Intervention Development (BID) Core to conduct clinical trials and...
This $1,177,500 federal Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) supports the Arizona State University (ASU) Roybal Center for Older Adults Living Alone with Cognitive Decline. The center will develop and conduct clinical trials of technology-enabled behavioral and lifestyle interventions to delay Alzheimer's disease and related dementias (ADRD) and improve quality of life in older adults living alone with cognitive decline,...
This federal Project Grant award, totaling $460,388, was provided by the National Institute on Aging (NIA) under the Aging Research (CFDA 93.866) program. The purpose of the award is to pilot test the "Promoting Positive Care Interactions (PPCI)" intervention, which aims to establish a feasible and culturally responsive approach to optimize care interactions between staff and residents with Alzheimer's disease and related dementias (ADRD) in assisted living facilities (ALFs). The key...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will provide $203,278 to Brandeis University to conduct research on the neurobiological mechanisms underlying daily life activity participation in older adults and its relationship to Alzheimer's disease pathology. The research will use behavioral, psychophysiological, neuroimaging, and naturalistic approaches to understand age-related shifts in motivation and neuromodulation that impact older...
This $2,366,213 federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) will fund the INLIFE (Individualized Lifestyle Change for Every Aging Brain) study. The study aims to harmonize and analyze participant-level data from 12 U.S. randomized controlled trials to examine how changes in lifestyle behaviors such as physical activity, cognitive activity, diet, and social engagement impact cognitive outcomes across diverse older adult populations....
The National Institutes of Health's National Institute on Aging awarded $256,331.40 under the Aging Research program (CFDA 93.866) to The Trustees of the University of Pennsylvania from February to October 2021. The project aims to develop novel machine learning algorithms and biomedical software to more accurately quantify brain aging and predict the onset of neurodegenerative diseases such as Alzheimer's. Specifically, the funding will support refining predictive models of the...
This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $835,056 to Trustees of Tufts College (Tufts University) to develop a multi-modal system of wearable biosensors and associated machine learning algorithms for the continuous monitoring of mobility and cognitive function in an aging population. The key products and services to be delivered under this award include: 1) a system of flexible, breathable, and inconspicuous eutectogel sensor patches...
This federal Project Grant award of $2,358,537.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports a research project titled "Epigenetic Aging, Cognitive Function and Exercise in Older Adults" at the University of Pittsburgh. The project aims to investigate the impact of exercise on epigenetic aging and its relationship to cognitive function, brain health, and Alzheimer's disease biomarkers in non-cognitively impaired older adults. The award period runs from...
This National Institute on Aging (NIA) Project Grant award (CFDA 93.866 - Aging Research) provides $154,858 to the University of Pittsburgh to explore the associations between a novel physical activity complexity metric and cognitive function, biomarkers, and brain structure in an older adult population. The study aims to (1) examine how physical activity complexity relates to cognitive performance and risk of mild cognitive impairment and Alzheimer's disease, (2) determine if low physical...
This Project Grant award of $4,787,820, provided by the National Institute on Aging (CFDA 93.866 Aging Research), supports a research project titled "PREDICT ADRD: PREDICTING THE EFFECTS OF DIAGNOSIS IN INDIVIDUALS ACROSS COUNTRIES AND TIME IN ADRD". The primary goals are to: 1) examine the relationship between cognitive decline and workforce exit for older adults in the U.S., England, and 28 European countries; 2) assess the concordance between survey-based cognitive tests and...
This $2,197,830 Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) will fund the Penn State Roybal Center for Promoting Adherence to Behavior Change and Enhancing Cognitive Function. The center aims to develop and test novel interventions to improve adherence to behavior change, particularly physical activity, and enhance cognitive function in middle-aged and older adults. Key objectives include conducting clinical trials to create scalable, principle-driven behavioral interventions leveraging consumer technology and AI, establishing evidence-based strategies for improving adherence, elucidating processes influencing adherence and cognition, and characterizing the effects of physical activity adherence on cognition. The award period runs from Aug 15, 2024 to Jun 30, 2029.