The University of California, San Francisco (UCSF) was awarded a $1,230,000 project grant from the National Institute on Aging (NIA) under the Aging Research Federal Grant Program (CFDA 93.866). The grant supports the development and testing of closed-loop digital interventions delivered through a remote clinical trials platform. The goal is to leverage technology to facilitate memory and cognitive function in older adults, particularly those at risk of Alzheimer's disease and related dementias. The 5-year project, running from August 2024 to May 2029, involves a Behavioral Intervention Development (BID) Core that will conduct clinical trials to produce implementable behavioral interventions, and an Administrative Core that will provide oversight, collaboration facilitation, and infrastructure support. The award builds on UCSF's longstanding expertise in administering large, collaborative grants focused on developing innovative solutions to address age-related cognitive decline.