Project Grant N660010912121

This $298,045 Project Grant award from the National Institutes of Health's National Center for Advancing Translational Sciences (CFDA 93.350) aims to establish and develop a high-throughput screening (HTS) assay to identify novel bacterial DNA gyrase poisoning inhibitors. The key products and services to be delivered under this one-year award include: Developing a unique HTS assay to rapidly discover bacterial DNA gyrase poisoning inhibitors from small molecule libraries. This assay will...

Federal Grant Award Summary SKM Instruments, LLC received a $797,550 Project Grant from the Centers for Disease Control and Prevention (CDC) under the Prevention of Disease, Disability, and Death by Infectious Diseases program (CFDA 93.084) to develop an ultra-rapid optical platform for antimicrobial susceptibility testing (AST) of pulmonary non-tuberculous mycobacterial (NTM) infections. The award, effective September 30, 2025, with a completion date of May 31, 2026, supports research and...

This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $305,000.00 to Resonantia Diagnostics, Inc. to develop a transformative diagnostic platform for rapid identification and antimicrobial susceptibility testing of pathogens. The project aims to achieve three key technical objectives: (1) demonstrate accurate antimicrobial susceptibility testing at very low pathogen loads, (2) validate testing...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 aims to develop a platform for detecting genetic antibiotic resistance motifs that can predict current and future susceptibility to therapeutics. The project will establish the feasibility of leveraging mutational signatures in bacterial DNA to identify antibiotic resistance status, including the potential for rapid development of multi-drug resistance. This approach...

This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to RT Microdx Inc. provides $274,362 to develop a novel molecular diagnostic platform for detecting respiratory diseases like strep throat. The platform aims to provide laboratory-quality accuracy for at-home use by non-healthcare professionals. Key technical objectives include optimizing the sensitivity of the platform's pH-sensitive polymer detection mechanism and ensuring robust performance at...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $4.76 million Project Grant to The Regents of the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support the Rapid Research for Diagnostics Development in TB Network: Episode 2 (R2D2 TB Network II). Awarded on September 23, 2025, with a completion date of August 31, 2030, this initiative addresses critical gaps in tuberculosis (TB) diagnostics in...

Federal Project Grant Award Summary Tufts Medical Center Parent, Inc. (Tufts Medical Center) received a $190,768 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 2, 2025, through August 31, 2028. The award funds development of a rapid transcriptomic assay for antimicrobial susceptibility testing (AST) of Mycobacterium abscessus, a nontuberculous mycobacterium...

National Jewish Health received a $429,546 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to evaluate antibiotic regimen efficacy for tuberculosis (TB) treatment. The award, effective August 8, 2025, through July 31, 2027, supports research utilizing SEARCH-TB, an RNA-sequencing platform designed to quantify drug-induced bacterial injury and physiological adaptations in Mycobacterium...

The National Science Foundation awarded PZA Innovation LLC a $270,509 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop reliable pyrazinamide susceptibility testing at neutral pH. The grant period runs from January 1, 2022 through October 31, 2023. Under this award, PZA Innovation LLC will deliver products and services focused on advancing science and engineering research and innovation leading to breakthrough technologies for national and...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $238,500 Project Grant under the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program to the University of California, San Diego (UCSD) to develop a novel electrochemical lateral flow assay (ELFA) for diagnosing tuberculosis (TB) from a single drop of blood. The objective is to create a highly sensitive and specific point-of-need TB detection test that can accurately distinguish active TB from...