Project Grant K99NS138684
- The National Institute of Neurological Disorders and Stroke awarded The Scripps Research Institute $710,155 on February 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate post-transcriptional mechanisms of cortical inhibitory interneuron development. The research focuses on identifying how microRNA-mediated regulation controls interneuron migration and specification during development. The work employs engineered...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded $153,560 to the Broad Institute, Inc. (doing business as Broad Institute of MIT and Harvard) on December 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining how excitatory neurons regulate interneuron fate, position, and survival during...
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of California, San Francisco $943,253 on January 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders grant program (CFDA 93.853, Assistance Listing R35NS142982). The award funds preclinical development of breakthrough immunotherapy for brain tumors, specifically malignant glioma. Research activities include developing neo-junction-targeting T-cell...
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded $445,500 to Cincinnati Children's Hospital Medical Center on July 25, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct preclinical research on microRNA-mediated regulation of IL-17A-associated neurodevelopmental defects induced by maternal immune activation. The...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Regents of the University of California, San Francisco $128,139 on September 23, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research to develop a multi-modal transcriptomic atlas of normal and diseased cerebral vasculature, with focus on mural cell biology in brain arteriovenous malformations (BAVMs). The research consists of two...
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of California, San Francisco $2,656,684 on February 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to discover and validate gene therapy and biologic delivery vectors for central nervous system diseases using physiologically maintained deceased human cadavers as a discovery platform. The award funds development of an...
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of California, San Francisco $190,080 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining the relationships between economic instability, epigenetic aging, and vascular contributions to cognitive impairment (VCID) across the adult lifecourse. The project applies causal inference methods...
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of California, San Francisco $595,208 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Assistance Listing Project Grant R01NS148534). The award funds research investigating striatal synaptic plasticity mechanisms underlying cognitive dysfunction in Parkinson's disease. The project examines circuit- and synaptic-level...
- The National Institute of Mental Health awarded The Regents of the University of California, San Francisco (UCSF) $568,746 on August 11, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate the cellular mechanisms by which autism-associated protein SYNGAP1 functions at the primary cilium. The funded research tests the hypothesis that autism spectrum disorder risk genes play pleiotropic roles across subcellular compartments, including functionally significant roles...
- The National Institute of Neurological Disorders and Stroke awarded the University of California, San Diego $119,286 on August 18, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the functional roles of microbial metabolites in HIV-associated neurocognitive disorders (HAND). The research integrates metabolomics, metagenomics, in vitro and in vivo assays, and computational approaches to address gaps in understanding...
The National Institute of Neurological Disorders and Stroke, an institute of the National Institutes of Health, awarded The Regents of the University of California, San Francisco $205,200 on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research into the role of microglia in cortical interneuron development in genetic and environmental disruptions associated with autism spectrum disorder. The work investigates how the brain's resident immune cells affect the development, migration, and network maturation of inhibitory cortical interneurons, which maintain cortical functional rhythms and neural circuit activity. The research employs neuroimmune organoids to explore microglia's role in neurogenesis and neuronal maturation within a human context, addressing gaps in understanding created by limited access to human brain tissue and incomplete recapitulation of human processes in animal models. Performance of the work occurs in San Francisco, California, with a period of performance from August 15, 2026, through August 31, 2028. This is a Project Grant, the assistance type for hypothesis-driven research under the NINDS program.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $205.2k | 8/14/26 |