Project Grant K23NS151370
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Regents of the University of California, San Francisco $128,139 on September 23, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research to develop a multi-modal transcriptomic atlas of normal and diseased cerebral vasculature, with focus on mural cell biology in brain arteriovenous malformations (BAVMs). The research consists of two...
- The National Institute of Neurological Disorders and Stroke awarded the University of California Irvine $863,500 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of vascular contributions to cognitive impairment and dementia due to cerebral microbleeds in the context of periodontitis. The project uses novel animal models of cerebral microhemorrhage to identify mechanisms linking dementia...
- The National Institute of Neurological Disorders and Stroke awarded the University of Washington $647,418 under Project Grant R01NS144133 on August 27, 2026, to investigate the interaction between atherosclerotic plaque composition, reduced brain perfusion, and cognitive decline in vascular cognitive impairment and dementia (VCID). The award funds research to identify and characterize two distinct mechanisms driving VCID in patients with asymptomatic carotid and intracranial atherosclerosis:...
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of California, San Francisco $2,656,684 on February 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to discover and validate gene therapy and biologic delivery vectors for central nervous system diseases using physiologically maintained deceased human cadavers as a discovery platform. The award funds development of an...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded Albany Medical College $1.951689 million on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of inflammation-resolution pathways to address vascular contributions to cognitive impairment and dementia (VCID) in the context of atherosclerosis....
- The National Institute on Aging awarded The Regents of the University of California, San Francisco $119,785 on March 1, 2026, under the Aging Research program (CFDA 93.866) to investigate the cerebellum's role in social cognitive deficits and clinical progression in behavioral variant frontotemporal dementia (BVFTD). The research characterizes cerebellar structural and functional relationships to social cognition in BVFTD across disease stages using cross-sectional neuroimaging data from...
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded the University of Cincinnati $654,628 on March 6, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to characterize the peripheral and immune-cell proteome in intracerebral hemorrhage patients and identify biomarkers and mechanisms associated with vascular cognitive...
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of California, San Francisco $595,208 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Assistance Listing Project Grant R01NS148534). The award funds research investigating striatal synaptic plasticity mechanisms underlying cognitive dysfunction in Parkinson's disease. The project examines circuit- and synaptic-level...
- The National Institute on Aging awarded the University of California, Davis $690,934 on March 1, 2026, under the Aging Research program (CFDA 93.866) to investigate subjective cognitive decline as an early risk indicator for Alzheimer's disease and related dementias across racially and ethnically diverse older adult populations. The research addresses a critical knowledge gap in existing literature, which has predominantly focused on White older adults. The project examines how subjective...
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of California, San Francisco $451,000 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Project Grant R21NS144615). The award funds development of genetic tools and methods for tracking brain lipids in vivo with subcellular precision. The recipient will create genetic approaches to tag lipid tails and track lipid...
The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of California, San Francisco $190,080 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining the relationships between economic instability, epigenetic aging, and vascular contributions to cognitive impairment (VCID) across the adult lifecourse. The project applies causal inference methods to analyze data from two established cohort studies: the Coronary Artery Risk Development in Young Adults (CARDIA) study, which captures young adulthood through middle age and measures subclinical VCID, and the Health and Retirement Study (HRS), a nationally representative cohort of older adults capturing middle to old age with clinical VCID measures linked to Centers for Medicare and Medicaid Services data. Both cohorts contain robust household-level wealth and income data and geocoded neighborhood-level economic data collected over time. The research addresses the higher risk of cerebrovascular disease and dementia in low-socioeconomic-status communities by exploring how sudden changes in wealth or income—beyond static socioeconomic measures—may accelerate epigenetic aging and increase VCID burden. Results are intended to inform public health policy addressing economic instability as a preventive intervention. Work is performed in San Francisco, California, with a period of performance from September 1, 2026, through August 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $190.1k | 8/18/26 |