This federal Project Grant award, valued at $146,816 and awarded on June 26, 2025, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The funding supports research at the University of California, San Diego (UCSD) to simultaneously measure synaptic and spiking activity in corticospinal projection neurons in the primary motor cortex during the learning...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund research to investigate the biophysical mechanisms that regulate axon morphology and function. The $375,835 award, effective September 1, 2024, will support a 5-year study conducted by the University of California, San Diego (UCSD) to determine how lipid composition and cytoskeletal structure influence axon shape, ion channel localization, and...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to investigate synaptic plasticity mechanisms that protect and refine local neural circuits. The $466,757 award to the University of Texas at Austin aims to advance understanding of how synapse structure supports learning and memory, with a focus on dendritic spines and the regulation of synaptic active zones. The research will use...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $706,959 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to the University of California, Davis. The 5-year grant, awarded on September 18, 2024, will support research to elucidate the molecular signaling mechanisms that regulate the growth, stabilization, and functional maturation of dendritic spines and their associated synapses during activity-dependent...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $781,119 to The Regents of the University of California, San Francisco (UCSF) to conduct research on "Dissecting the Circuits and Population Dynamics that Represent Unconditioned and Conditioned Stimuli in the Ventral Hippocampus." The 5-year project, which begins on March 1, 2025 and concludes on December 31, 2029, aims to leverage...
The National Institute of Mental Health (NIMH) awarded a $3,360,283 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the Massachusetts Institute of Technology (MIT) to study the role of top-down dendritic processing in credit assignment and cortical dynamics. The 4-year research project, which began on July 18, 2024 and is scheduled to conclude on April 30, 2028, aims to establish the relationship between single-neuron dendritic integration and circuit dynamics,...
The National Institute of Mental Health (NIMH) awarded a $692,043 Project Grant (CFDA 93.242 Mental Health Research Grants) to The Regents of the University of California, San Francisco (UCSF) to investigate the role of presynaptic homeostatic plasticity in mental health disorders, including autism and intellectual disability. The research aims to establish a mechanistic framework linking homeostatic plasticity to the genetic underpinnings of these conditions, with the goal of developing...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $234,000.00 to investigate how inhibitory synapses in the brain regulate the structure and function of excitatory synapses throughout brain development. The research aims to elucidate the cellular and synaptic mechanisms by which inhibitory GABAergic synapses heterosynaptically modulate excitatory glutamatergic synapse formation and elimination....
The U.S. National Institute of Mental Health (NIMH) awarded a $446,627 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the University of California, San Diego (UCSD) to investigate orientation tuning and directional encoding in the subiculum region of the brain. The research project aims to systematically examine how individual subiculum neurons encode multiple directions of travel within constrained navigation environments. The work will have implications for understanding the...
This $237,750 federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research at the University of California, Merced to elucidate the role of the BAF chromatin remodeling complex in experience-induced neuronal gene transcription and synapse maturation, with implications for understanding autism spectrum disorders (ASD). The key objectives are to determine if the neuronal BAF (NBAF) complex, and...