Project Grant K99HD119229
- The National Institute of Child Health and Human Development awarded The Regents of the University of Colorado, doing business as University of Colorado-Denver, $669,594 on June 17, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to investigate circulating extracellular vesicles as functional biomarkers of maternal mental and physical health in pregnancy and postpartum, with focus on women with high levels of adverse childhood experiences....
- Federal Grant Award Summary The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded the University of Colorado-Denver a $2.26 million Project Grant (CFDA 93.865: Child Health and Human Development Extramural Research) on September 15, 2025, for research investigating inflammatory signaling mechanisms across the maternal-fetal interface. The research addresses critical gaps in understanding how inflammatory signals transfer through the placenta during...
- Federal Grant Award Summary The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded $429,000 in Project Grant funding to the University of Colorado-Denver for research conducted under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award was obligated on August 6, 2025, with a project completion date of July 31, 2027. This R21 mechanism grant supports research utilizing induced pluripotent stem cell (iPSC)...
- The National Institute of Child Health and Human Development awarded The Regents Of The University Of Colorado (doing business as University Of Colorado-Denver) $636,728 for a Project Grant in Child Health and Human Development Extramural Research (CFDA 93.865) effective August 4, 2026. The award funds a multicenter prospective study measuring physical activity recovery in children who survive acute respiratory disease requiring invasive mechanical ventilation in pediatric intensive care...
- The National Institute of Child Health and Human Development awarded The Regents of The University of Colorado (University of Colorado-Denver) $584,626 on July 8, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to define mechanisms regulating functional regionalization of the mammalian ovary during fetal and perinatal development. Using three-dimensional imaging, computational analyses, and single-cell-scale spatial transcriptomics, the research...
- The National Institute of Child Health and Human Development awarded the Regents of the University of Colorado, doing business as University of Colorado-Denver, $749,653 on June 25, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award funds development and validation of screening and diagnostic criteria for pediatric sepsis tailored to emergency care settings. The project will develop suspected sepsis criteria to identify children at risk for...
- The National Institute of Child Health and Human Development awarded The Regents Of The University Of Colorado, doing business as University Of Colorado-Denver, $114,040 on June 23, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to evaluate the impacts of paid family leave on family violence morbidity and mortality through a Career Development Award (K01). The recipient will conduct three research aims: evaluate the completeness of a novel multi-year...
- The National Institute of Child Health and Human Development awarded The Regents of the University of Colorado $430,375 on August 27, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate lipid droplet regulation and function in the developing neural tube. The research addresses how embryonic neural tubes utilize lipids to control development and how maternal metabolic disorders—type 2 diabetes and obesity—increase the risk of neural tube...
- The National Institute of Child Health and Human Development awarded The Regents of the University of Colorado (University of Colorado-Denver) $124,125 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the role of the Hedgehog signaling pathway—specifically GLI2—in endometrial remodeling and placental development. The project uses a mouse model with conditionally deleted uterine GLI2 to examine how the Hedgehog signaling...
- The National Institute of Child Health and Human Development awarded The Regents of the University of Colorado, doing business as University of Colorado-Denver, $163,825 under the Child Health and Human Development Extramural Research program on June 2, 2026, to develop and validate trajectory-based phenotypes of pediatric septic shock and test targeted treatment interventions. The recipient will use trajectory modeling to derive and validate trajectory-based phenotypes (TBPs) of pediatric...
The National Institute of Child Health and Human Development awarded The Regents Of The University Of Colorado, doing business as University Of Colorado-Denver, $114,268 in project grant funding on August 25, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award funds research investigating how placental proteins influence prematurity outcomes. The project tests the hypothesis that proteins secreted by the preterm placenta—with documented involvement in brain, lung, and liver development—improve outcomes in prematurely born animals, using induced preterm delivery models. The researcher identified 142 proteins secreted by the human placenta before 32 weeks of gestation; the work examines whether proteins associated with neurogenesis, lung development, and angiogenesis are essential for normal fetal organ development and whether their loss in premature infants contributes to neonatal complications including intraventricular hemorrhage, respiratory distress syndrome, necrotizing enterocolitis, and long-term sequelae such as chronic lung disease and neurodevelopmental dysfunction. Performance extends from the award date through July 31, 2028. Work is performed in Aurora, Colorado. University Of Colorado-Denver is a child entity under The Regents Of The University Of Colorado system.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $114.3k | 8/25/26 |