This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the CFDA Program "Discovery and Applied Research for Technological Innovations to Improve Human Health", is funding the development of a passive, shunt-mountable intracranial pressure (ICP) sensor that can be wirelessly interrogated using ultrasound. The total award amount is $131,085, with a project period from June 9, 2025 to May 31, 2027. The key objectives are to: 1) optimize the sensor design through mathematical modeling and simulations, 2) validate the sensor's wireless ultrasound localization and communication capabilities, and 3) miniaturize the sensor electronics and package it for implantable use, culminating in testing in a hydrocephalus rodent model. This work addresses the critical need for a reliable, non-invasive method to monitor ICP and diagnose shunt failure in hydrocephalus patients. The innovative approach uses acoustic frequency combs to sense and communicate ICP through the skull, providing a fundamentally new tool for longitudinal ICP monitoring.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $131.1k | 6/9/25 |