This federal Project Grant award, valued at $154,861 and provided by the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research), aims to advance the integration of social and medical care to promote health equity among children with asthma. The key products and services to be delivered under this grant include: Developing a population-based machine learning model to predict risk of asthma-related hospitalization among children in Washington, D.C. using social...
The National Heart, Lung, and Blood Institute (NHLBI), under CFDA 93.837 - Cardiovascular Diseases Research, awarded a $387,116 Project Grant to the University of South Florida. The 5-year grant, effective May 1, 2025, supports research to define the neural mechanisms by which house dust mite (HDM) exposure triggers airway hyperreactivity, a key characteristic of asthma. The research aims to identify the specific sensory nerve subtypes and signaling pathways activated by HDM that lead to...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $706,806 Project Grant under CFDA 93.837 (Cardiovascular Diseases Research) to Elimu Informatics Inc., a small business software company in California. The grant funds the design, development, and evaluation of TIBSA (Tailored Interoperable Guideline-Based Clinical Decision-Support System for Asthma), a clinical decision support application that incorporates the 2020 NHLBI asthma management guidelines, patient-specific data,...
This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $740,709 to the University of Utah to conduct research on how early-life viral infections can lead to the development of childhood asthma. The key objectives are to define the cellular and molecular mechanisms by which viral-induced inflammation programs hyperactivated type 2 innate lymphoid cells (ILC2s) in the lung, and determine if these hyperactivated ILC2s...
This $673,581 Project Grant awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to assess disparities in asthma care between Latino and non-Hispanic white adults, and identify the social determinants of health that may underlie these disparities. The grantee, Ochin, Inc., a nonprofit health IT collaborative based in Portland, Oregon, will leverage a large national dataset of electronic health records from...
The U.S. National Heart, Lung, and Blood Institute (NHLBI) awarded a $802,500 Cooperative Agreement grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the Children's Hospital Medical Center in Cincinnati, Ohio. The grant supports the construction of a multi-scale 3D AI-powered map of genetic factors and cellular interactions driving normal and aberrant lung development in childhood interstitial lung disease (CHILD). The project will leverage single-cell and spatial...
This $177,403 Project Grant was awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research (CFDA 93.837) program. The funding supports research to disentangle the heterogeneity of asthma, identify distinct asthma endotypes, and investigate biological mechanisms underlying established risk factors. The project will utilize multi-omics data from three cohorts of asthmatic children to analyze the interplay between genetic, epigenetic, and metabolomic...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $498,991.40 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of Arkansas. The grant, effective January 2, 2025 through December 31, 2027, will support the development of microphysiological systems to investigate molecular pathways and cardiomyocyte function in response to hypoxic cardiac injury associated with myocardial infarction and ischemia-reperfusion injury. The project aims to...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $1,401,548 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of Arizona. The grant, titled "Breathing Easier in Schools: Enhancing Adoption, Fidelity, and Effectiveness of the SAFE School Program through Innovation Implementation Strategies," aims to explore three implementation strategies to support the adoption, maintenance, and effectiveness of a school-based stock...
The Project Grant award K23HL163253, totaling $178,783, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The award will support Dr. Pappalardo's research to understand barriers and develop targeted implementation strategies for school-based stock inhaler programs, with the goal of improving asthma management and reducing health disparities. The grant will fund a community-engaged, implementation science...