Project Grant K01HL169756
Award Date
9/1/24
Completion Date
8/31/29
Dollars Obligated
$177K
Federal Agency
National Heart Lung and Blood Institute
Federal Grant Program
93.837
Assistance Type
Project Grant
Place of Performance
Boston, MA 02115, USA
Similar Awards
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under CFDA Program 93.837 - Cardiovascular Diseases Research, will provide $246,000.00 to the University of Chicago to investigate the immune cell landscape in Amish and Hutterite children and its relationship to asthma risk. The researchers will leverage the natural environmental differences between these two farming populations to generate multi-omic datasets characterizing the transcriptional and...
This federal Project Grant award, valued at $154,861 and provided by the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research), aims to advance the integration of social and medical care to promote health equity among children with asthma. The key products and services to be delivered under this grant include: Developing a population-based machine learning model to predict risk of asthma-related hospitalization among children in Washington, D.C. using social...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $732,225 to investigate the role of mitochondrial DNA (mtDNA) variants in the pathogenesis of asthma. The research aims to: 1) identify associations between mtDNA single nucleotide variants (SNVs) and asthma risk/traits, and examine how risk variants influence mitochondrial function in cells from asthmatic and healthy individuals, and 2)...
This $673,581 Project Grant awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to assess disparities in asthma care between Latino and non-Hispanic white adults, and identify the social determinants of health that may underlie these disparities. The grantee, Ochin, Inc., a nonprofit health IT collaborative based in Portland, Oregon, will leverage a large national dataset of electronic health records from...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $616,814 to the President and Fellows of Harvard College, Harvard T.H. Chan School of Public Health, to conduct research on the role of microRNAs in regulating airway smooth muscle function and their contribution to asthma. The overarching goal is to establish the in vivo impact of key microRNAs in regulating airway smooth muscle proliferation,...
This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $740,709 to the University of Utah to conduct research on how early-life viral infections can lead to the development of childhood asthma. The key objectives are to define the cellular and molecular mechanisms by which viral-induced inflammation programs hyperactivated type 2 innate lymphoid cells (ILC2s) in the lung, and determine if these hyperactivated ILC2s...
This Project Grant award for $355,935 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research federal grant program (CFDA 93.837) supports the development of a novel, oral immunoregulatory therapeutic for the treatment of asthma. The primary objectives are to characterize the therapeutic efficacy and dosing regimen of the compound in mouse models of asthma, and to evaluate its ability to modulate immune function and suppress inflammation in human...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $164,453 Project Grant (CFDA 93.837 - Cardiovascular Diseases Research) to the Arkansas Children's Research Institute (ACRI) on September 15, 2024. The grant will fund a 4-year research project titled "Multifactorial Asthma Determinants in Underresourced Pediatric Populations." The project aims to investigate disparities in pediatric asthma prevalence and morbidity, particularly among racial/ethnic minority and rural,...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $636,843 to The Regents of the University of California, San Francisco (UCSF) to conduct research on targeting the stromal niche for tissue-resident lymphocytes in asthma. The research aims to characterize a targetable stromal factor that alters immune cell accumulation in the lung and define the downstream effects on airway epithelial...
The National Heart, Lung, and Blood Institute (NHLBI), under CFDA 93.837 - Cardiovascular Diseases Research, awarded a $387,116 Project Grant to the University of South Florida. The 5-year grant, effective May 1, 2025, supports research to define the neural mechanisms by which house dust mite (HDM) exposure triggers airway hyperreactivity, a key characteristic of asthma. The research aims to identify the specific sensory nerve subtypes and signaling pathways activated by HDM that lead to...