Project Grant K23HD119310
- Federal Grant Award Summary The University of Southern California received a $747,000 Project Grant awarded on August 1, 2025, from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The three-year project, extending through July 31, 2028, will conduct comprehensive research investigating the genetic and genomic influences on human milk composition and their impacts on infant health. The...
- Federal Grant Award Summary The University of Washington received a $161,892 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 9, 2025, through August 31, 2030. This research project will compare the microbial composition and human milk oligosaccharide (HMO) profiles of parent's own milk (POM) versus donor human milk (DHM) to understand their...
- Federal Project Grant Award Summary Cincinnati Children's Hospital Medical Center received a Project Grant award of $165,240 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award, effective June 1, 2026, through May 31, 2030, supports research examining the effects of bioactive components in donor milk on preterm infant growth. The research addresses the critical clinical problem...
- Federal Grant Award Summary The University of California, San Diego received a $438,375 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) for research investigating the role of milk extracellular vesicles (MEVs) in offspring metabolic programming. The award, effective June 10, 2026, through May 31, 2028, supports investigator-initiated research examining how maternal...
- Federal Grant Award Summary The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded Icahn School of Medicine at Mount Sinai a Project Grant totaling $751,204 under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the genetic and genomic mechanisms underlying human lactation disorders. The award, effective June 1, 2026 through May 31, 2031, funds comprehensive whole exome sequencing (WES) research...
- Federal Grant Award Summary Baylor College of Medicine received a $425,015 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) with an award date of August 1, 2025, and completion date of July 31, 2027. The research project investigates interindividual epigenetic variation at birth and its association with subsequent risk of dysbiosis and necrotizing enterocolitis (NEC) in...
- Federal Project Grant Award Summary The Medical University of South Carolina received a $747,003 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective July 1, 2025 through June 30, 2028. This award funds the development and evaluation of Project Support, a brief telehealth intervention designed to enhance supportive parenting and improve treatment engagement among...
- Summary The National Institute of Child Health and Human Development awarded a $119,544 Project Grant to The Washington University (Office of Sponsored Research Services) for research investigating the role of cell-free mitochondria in breast milk to support neonatal metabolism. The award was obligated on June 1, 2026, with an ultimate completion date of May 31, 2028. Funded under CFDA 93.865 (Child Health and Human Development Extramural Research), this investigator-initiated research project...
- Federal Grant Award Summary The National Institute of Child Health and Human Development awarded a $448,182 Project Grant to The Research Foundation For The State University Of New York (SUNY at Binghamton) under the Child Health and Human Development Extramural Research program (CFDA 93.865) for a project period from September 1, 2025 through March 31, 2027. The award funds the development of a novel physiologically based pharmacokinetic (PBPK) modeling approach to improve prediction of...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded The Medical College of Wisconsin, Inc. a $722,631 Project Grant on June 17, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to validate the causality of disputed mitochondrial variants associated with inborn errors of metabolism. The research addresses primary mitochondrial disease (PMD), a multi-systemic disorder caused by impaired mitochondrial...
The National Institute of Child Health and Human Development awarded The Medical University of South Carolina a $183,168 Project Grant (CFDA 93.865 – Child Health and Human Development Extramural Research) effective June 4, 2026, with completion scheduled for May 31, 2029. The grant funds research investigating lipid degradation in human donor milk and its impact on preterm infant gastrointestinal outcomes, specifically necrotizing enterocolitis (NEC). The research will evaluate how fatty acid-protein complexes and secondary lipid oxidation products in stored milk contribute to intestinal stress and mitochondrial dysfunction in preterm infants, utilizing advanced laboratory models including human-derived enteroids and prospective patient data from MUSC's pediatric biorepository. The research deliverables include comprehensive characterization of lipid degradation in banked donor milk using liquid chromatography-mass spectrometry and Fourier-transform mass spectrometry analyses, assessment of mitochondrial dysfunction endpoints in preterm enteroid models exposed to lipid oxidation products, and investigation of barrier integrity effects from milk metabolites. The findings are expected to inform new milk storage protocols and recommendations to maintain optimal quality for clinical use in neonatal care, ultimately reducing the risk of life-threatening gastrointestinal complications in preterm populations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $183.2k | 6/9/26 |