This Project Grant award, totaling $524,390.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award will fund a randomized clinical trial to evaluate the effects of a combined sleep health and circadian timing intervention on insulin resistance, glycemic control, and vascular function in adolescents with type 1 diabetes. The research aims to...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $190,686 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Southern California. The project aims to study the relationship between sleep characteristics, hypothalamic signaling, and metabolic risk in children over a 2-year longitudinal study. The research will utilize the established BrainChild cohort of 200 children aged 7-10 to...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $684,116 to the University of Illinois to examine the mechanisms by which improving sleep regularity through behavioral sleep intervention affects glycemic control and cardiovascular disease (CVD) risks in adults with type 1 diabetes (T1D). The study aims to conduct a 4-week behavioral...
This federal Project Grant award of $691,124 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will support research to examine the links between circadian disruption and cardiometabolic risk during the transition from adolescence to young adulthood. The research aims to: 1) Test the hypothesis that persistent circadian disruption from adolescence to young adulthood is related to the development of metabolic syndrome; 2)...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $772,246 to The Salk Institute for Biological Studies to conduct a clinical study on the effects of time-restricted eating (TRE) and TRE with a low-glycemic snack (TRE-LGS) on the health of night shift workers. The study will recruit overweight and obese adult night shift workers and...
This federal Project Grant award, with an ID of DP1DK139804, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $271,625 award to Emory University is focused on understanding the impact of HIV co-infections and comorbidities on circadian rhythm in the liver. Using innovative cell culture and in vivo systems, the project aims to investigate how disruption...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859) provides $435,126 to the University of Chicago to study the biophysical basis of circadian rhythms and their connection to metabolism and fitness. The research aims to quantify the relationship between the circadian clock and the external environment required for optimal fitness, and to reconstitute an oscillatory system with...
This Project Grant award, with a total funding of $211,590, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research project aims to investigate the real-time impact of psychosocial factors, such as mood, stress, and social interactions, on blood glucose levels among 50 adults with type 1 diabetes. The research will utilize Ecological Momentary...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to elucidate the mechanisms by which morning insulin delivery impacts hepatic glucose metabolism later in the day. The $106,188 award will fund studies using the conscious dog model to investigate how morning hyperinsulinemia generated by peripheral (vs. portal vein)...
This $148,568 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to investigate the physiological regulation of energy intake during meals following weight loss. The research will leverage data from two ongoing NIDDK-funded studies - the ARROW study (R01DK114272) and the TIME2EAT study (R01DK132372) - to analyze energy balance, gut hormone...