Project Grant R01HL174738

Award Date 9/15/24
Completion Date 8/31/29
Dollars Obligated $684K
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
Chicago, IL 60612, USA
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This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) provides $524,390 to the University of Colorado-Denver to study the relationship between sleep health, circadian timing, and cardiometabolic risk in adolescents with type 1 diabetes. The research aims to utilize a combined sleep health and circadian timing intervention as a mechanistic probe to...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will provide $688,800.00 to the University of Chicago to investigate the role of obstructive sleep apnea (OSA) in glycemic dysregulation among adults with type 1 diabetes. The research study aims to determine how OSA impacts glycemic control in this population and examine the underlying...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under CFDA Program 93.837 - Cardiovascular Diseases Research, provides $691,124 to the Regents of the University of Michigan to study the relationship between circadian disruption and cardiometabolic risk during the transition from adolescence to young adulthood. The research aims to: 1) Test the hypothesis that persistent circadian disruption from adolescence to young adulthood is related to the...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) provides $211,590 to Carnegie Mellon University to conduct research on the time-varying psychosocial influences of blood glucose among adults with type 1 diabetes. The 18-month project will combine ecological momentary assessments and continuous glucose monitoring data from 50 participants to investigate how mood, stress, and social interactions impact blood glucose outcomes in...
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The grant will fund a 4-week behavioral sleep stability intervention in 80 adults with type 1 diabetes and irregular sleep patterns. The study will assess changes in circadian regulation, glycemic control, and cardiovascular outcomes, including measurements of melatonin levels, rest-activity rhythms, endothelial function, blood pressure, and insulin sensitivity. A sub-award of $113,544 to the University of Utah will support the involvement of a sleep medicine expert to advise on the study protocol and data collection. The overarching goal is to advance the understanding of how improving sleep regularity can influence glycemic control and cardiovascular risk in this population.

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