This federal Project Grant award of $200,385 from the National Institute on Aging (CFDA 93.866 - Aging Research) to the University of California, San Diego (UCSD) will investigate the association between hearing impairment, hippocampal function, and memory in middle-aged and older adults. The central hypothesis is that hearing impairment is linked to poorer hippocampal function and memory performance. The project aims to use UK Biobank data to analyze the relationship between hearing, hippocampal activity, and memory, as well as collect pilot data examining associations between hearing impairment, hippocampal fMRI activation, amyloid-beta deposition, and memory in 30 cognitively normal older adults. The findings are expected to provide critical evidence on the connection between hearing impairment and dementia risk, and inform future hearing-based interventions as part of a comprehensive approach to reducing Alzheimer's disease risk. The award will support the career development of the Principal Investigator, Dr. Megan Fitzhugh, toward becoming a leading researcher at the intersection of auditory neuroscience and Alzheimer's disease.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $200.4k | 5/1/25 |