Project Grant R01AG085277

Award Date 9/1/24
Completion Date 6/30/29
Dollars Obligated $1.5M
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Iowa City, IA 52242, USA
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This $295,825 Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) will support the development of a smartphone-based machine learning software system to enhance speech and reduce background noise for over-the-counter hearing aid devices. The goal is to improve the accessibility, affordability, and acceptance of hearing aids for underserved rural and minority populations who currently face significant barriers to obtaining effective hearing care. The funding will...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $2,433,859 supports research at The Johns Hopkins University to investigate age-related hearing loss and cognitive decline. The key objectives are to study the molecular, cellular, and connectivity changes in the central auditory system during normal aging and Alzheimer's disease, with the goal of developing targeted therapeutic strategies. The research integrates single-cell sequencing,...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will provide $200,385 to the University of California, San Diego (UCSD) to investigate the association between hearing impairment, hippocampal function, and memory in middle-aged and older adults. The overarching goal is to better understand how hearing impairment may be a modifiable risk factor for Alzheimer's disease and dementia. Specifically, the funded project will leverage data from the...
This Project Grant award from the National Institute on Aging (CFDA 93.866, Aging Research) will fund a $472,172 study by Kaiser Foundation Hospitals to evaluate the associations between hearing loss and cognitive and brain health outcomes in middle-aged adults. The study will leverage data from the Coronary Artery Risk Development in Young Adults (CARDIA) longitudinal cohort, including measures of audiometric hearing loss, cognitive test scores, and structural brain MRI. The goals are to...
This federal Project Grant award of $477,660 from the National Institute on Deafness and Other Communication Disorders (CFDA 93.173 - Research Related to Deafness and Communication Disorders) supports research to investigate age-related brain differences that affect speech recognition in older adults. The primary objectives are to characterize how quickly older adults accumulate sensory evidence and how much evidence they require to make speech recognition decisions, and to link these perceptual...
This $443,758 Project Grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) to Northwestern University aims to evaluate the use of over-the-counter (OTC) hearing aids for improving communication outcomes in older adults with mild cognitive impairment (MCI) or early Alzheimer's disease and related dementias (ADRD). The study will run from September 2023 to August 2025. Under this award, Northwestern University will lead a randomized trial to compare the communication...
The University of Iowa received a $1,199,085 project grant award from the National Science Foundation (NSF) Division of Computer and Network Systems under the CFDA program "Computer and Information Science and Engineering". The funding supports the development of new signal processing algorithms and configuration methods to personalize hearing aids and improve speech understanding, sound quality, and user satisfaction for individuals with hearing loss. The project aims to create two...
This federal Project Grant award of $610,725.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The grant will fund research at the University of Pittsburgh to investigate physiological mechanisms that contribute to suprathreshold deficits in speech understanding for individuals with sensorineural hearing loss. The key research activities include:...
This Project Grant awarded by the National Institute on Aging (NIA), under CFDA 93.866 Aging Research, aims to investigate the role of language acculturation in the association between hearing loss and cognitive function among Hispanic adults in the United States. The $675,469 award, effective September 1, 2024 through May 31, 2026, will be administered by The Johns Hopkins University. The research project has three specific aims: 1) Examine whether the association between hearing loss and...
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This federal Project Grant award, funded by the National Institute on Aging (CFDA 93.866 - Aging Research), is focused on understanding the effectiveness of cochlear implants and hearing aids in real-world settings for older adults with age-related hearing loss (ARHL), both with and without mild cognitive impairment or dementia.

The $1,495,307 award, which runs from September 1, 2024 to June 30, 2029, will collect real-world data via a smartphone ecological momentary assessment (EMA) system to assess outcomes across auditory function, cognitive performance, social interaction, and psychosocial well-being. The study will compare cross-sectional and longitudinal effects of cochlear implants versus hearing aids in ARHL patients with and without cognitive impairment. The University of Iowa is the primary grantee, and they have a sub-award with the University of Maryland, College Park to support data analysis and machine learning model development for the project.

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