Project Grant K18AG095816
Award Date 8/15/25
Completion Date 5/31/27
Dollars Obligated $209K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Louisiana, USA
Similar Awards
- The National Institute on Aging (NIA) awarded a $689,525 Project Grant under the Aging Research Federal Grant Program (CFDA 93.866) to New York University (NYU) to investigate the integration of cell-specific microstructure within long-range brain networks in the macaque monkey. The project aims to disentangle cell-type specific signatures of brain microstructure using in vivo MRI techniques and determine how these signatures vary across individuals. This work will contribute to a...
- This Project Grant award from the National Institute on Aging's (NIA) Aging Research Federal Grant Program (CFDA 93.866) is funding a $109,595 project at the University of California, Davis to characterize a novel non-human primate model of Alzheimer's disease. The project aims to perform comprehensive microscopic analyses to determine the patterns of tau-based neuropathology, neuronal loss, synaptic health, and neural circuit functionality in the brains of rhesus macaques with progressive tau...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to the Trustees of Boston University, doing business as Boston University Medical Campus, provides $2,330,859.00 in funding to study age-related changes in brain network connectivity and their relationship to cognitive decline. The 3-year project aims to use multimodal neuroimaging, single-cell transcriptomics, electrophysiology, and neural tract-tracing in a rhesus monkey model to delineate how...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $126,956.00 to the University of California, San Diego (UCSD) to conduct research on identifying mechanisms of adult neurogenesis in the aging brain. The key objectives of this project are to: Utilize single cell spatial transcriptomics to define the pathways of generating new neurons in aged neurogenic niches following transient, antisense oligonucleotide-mediated suppression of the PTBP1...
- This federal Project Grant award for $528,876, provided by the National Institute on Aging (CFDA 93.866 Aging Research), supports research to investigate the cis- and trans-genetic regulation of brain transcriptomics and proteomics associated with Alzheimer's disease (AD) and AD-related dementias (ADRD). The key goals of the project are to: Estimate genome-wide cis- and trans-acting quantitative trait loci (QTLs) effects for transcriptome-wide genes and proteome-wide proteins across 4 brain...
- This $1,554,682 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will fund the development of three new multi-modal atlases based on high-resolution Human Connectome Project (HCP) data. The objectives are to: 1) Create a new data-driven atlas of spatially overlapping weighted grey-matter functional networks, 2) Develop a new atlas of white matter tracts and their corresponding grey matter projection territories, and 3) Complete a semi-automated...
- The University of Massachusetts Medical School (UMass Medical) was awarded a $1,507,500 Project Grant from the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866) to conduct a study on spatial single-cell analysis of somatic mutations in the human brain during aging and neurodegeneration. The goal is to develop and apply new single-cell whole-genome sequencing methods to study somatic mutations in neurons from late-stage Alzheimer's disease and...
- The National Institute on Aging (NIA) awarded a $773,816 project grant under the Aging Research federal grant program (CFDA 93.866) to the University of California, Irvine (UCI) to conduct comparative studies on new tau-directed Alzheimer's disease (AD) and AD-related dementias (ADRD) mouse models and human AD/ADRD brain tissues. The project aims to generate single-cell spatial proteo-transcriptomics maps to molecularly characterize aberrant RNA splicing and abnormal protein products in specific...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $1,018,778 to The Lieber Institute for Brain Development (LIBD) to generate spatially-resolved, transcriptome-wide gene expression profiles of the human dentate gyrus across the lifespan. The project aims to characterize developmental and age-related changes in gene expression within specific subregions of the hippocampus, a critical brain structure involved in learning, memory, and...
- This Project Grant award of $437,875 from the National Institute on Aging's Aging Research program (CFDA 93.866) will fund a 2-year research project at the University of California, San Diego to quantify neurovascular protein lifetimes in the central nervous system under healthy, aging, and Alzheimer's disease conditions. The key objectives are to generate a comprehensive atlas of neurovascular protein lifetimes and identify changes associated with aging and Alzheimer's disease. The project will...