Project Grant K08NS135120
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $1,375,478 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the J. David Gladstone Institutes in California. This grant funding supports a multidisciplinary research program to study the role of neurovascular dysfunction in neurodegeneration, CNS repair, and glial cell biology. Key research activities include in vivo two-photon and super-resolution...
- This $4,164,187 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to develop antigen-directed therapies for autoantibody associated neuroinflammatory diseases. The project aims to facilitate the discovery of autoantibodies directed to cell surface antigens, characterize their specificity, and generate recombinant human...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $737,881 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) to conduct secondary analyses of the ACTG IMAGINE-TBM clinical trial. The objectives are to use metagenomics and host transcriptomics to improve diagnosis of tuberculous meningitis (TBM) and assess treatment response in this...
- This $198,928 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant will support research at the University of California, San Francisco to elucidate the cellular mechanisms underlying central nervous system injury and progression in multiple sclerosis. Key objectives include determining the role of astrocyte response,...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025 for $1,180,687. The purpose of this 8-year project is to investigate how neural stem cell niches transition from embryonic to postnatal stages in the human forebrain, with a focus on characterizing the different neural...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $698,390 to the Regents of the University of California at Riverside to conduct research aimed at harnessing innate immunity to control the neuroinflammatory HIV reservoir. The key objectives are to investigate how HIV infection triggers an interferon (IFN) response, how HIV...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $209,910 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025. The grant supports a 2-year research project to conduct mechanistic and functional genomic analysis of genes associated with meningioma radiotherapy response. The goal is to better understand the biology of...
- This federal Project Grant award of $238,410 from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders will fund a 5-year mentored research project led by Dr. Sarah Kaufman at the University of California, San Francisco. The project aims to elucidate the mechanisms underlying tau aggregation and neurotoxicity in Alzheimer's disease and frontotemporal lobar degeneration. The research...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,025,015 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Scintillon Institute in California. The grant, awarded on August 11, 2025, supports the development of a next-generation preclinical model of NeuroHIV that better recapitulates the neuro-immune-vascular system interactions in the context of antiretroviral therapy-mediated HIV suppression....
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $125,724 project grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on January 23, 2025. The project, titled "Hypoxia-Induced Misdirection: Understanding Postnatal Inhibitory Interneuron Migration in Neonatal Hypoxic Injury", aims to use computational approaches to identify altered...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $239,490 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco. The goal of this 5-year research project is to train Dr. Sasha Gupta to become an independently funded investigator studying cellular therapeutics for the treatment of autoimmune and infectious neurologic conditions. Specifically, the research aims to identify, isolate, and sequence T cell receptors that are highly specific for JC virus antigens and have antiviral activity, with the goal of advancing the development of anti-JC virus T cell therapies to treat progressive multifocal leukoencephalopathy. This project will provide Dr. Gupta with training in virology, immunology, bioinformatics, and the clinical implementation of cellular therapies through coursework, mentored practical training, and guidance from an exceptional team of mentors and collaborators.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $239.5k | 8/13/25 |